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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
19.39
Human Site:
S892
Identified Species:
32.82
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
S892
R
G
A
L
R
L
P
S
F
K
V
K
R
K
E
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S892
R
G
A
L
R
L
P
S
F
K
V
K
R
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
E595
A
L
Y
T
Q
G
Q
E
G
R
G
A
Y
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S952
R
G
A
I
R
L
P
S
F
K
V
K
R
K
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
A552
T
P
V
V
D
E
P
A
M
V
A
E
T
V
A
Chicken
Gallus gallus
Q5F3P8
2008
223067
S945
R
G
A
I
R
L
P
S
F
K
V
K
R
K
E
Frog
Xenopus laevis
Q66J90
1938
216239
S910
R
G
A
I
R
L
P
S
F
K
V
K
R
K
E
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
A948
S
S
S
K
R
R
P
A
R
P
L
E
L
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
S860
Q
E
E
M
V
Q
R
S
D
S
D
K
E
D
S
Honey Bee
Apis mellifera
XP_395451
1406
159180
P671
R
A
S
M
P
K
M
P
S
F
R
R
K
I
K
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
L772
K
K
R
M
M
D
E
L
S
R
K
V
A
E
D
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
P1099
M
P
P
P
S
I
G
P
D
G
L
P
D
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
N345
N
K
H
S
I
L
N
N
I
I
S
K
F
V
E
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
E578
S
E
K
R
P
P
P
E
H
R
Q
R
D
D
Q
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
0
N.A.
93.3
N.A.
N.A.
6.6
93.3
93.3
13.3
N.A.
13.3
6.6
0
0
P-Site Similarity:
100
100
N.A.
13.3
N.A.
100
N.A.
N.A.
26.6
100
100
40
N.A.
26.6
40
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
36
0
0
0
0
15
0
0
8
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
0
15
0
8
0
15
22
8
% D
% Glu:
0
15
8
0
0
8
8
15
0
0
0
15
8
8
43
% E
% Phe:
0
0
0
0
0
0
0
0
36
8
0
0
8
8
0
% F
% Gly:
0
36
0
0
0
8
8
0
8
8
8
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
22
8
8
0
0
8
8
0
0
0
8
0
% I
% Lys:
8
15
8
8
0
8
0
0
0
36
8
50
8
36
15
% K
% Leu:
0
8
0
15
0
43
0
8
0
0
15
0
8
0
0
% L
% Met:
8
0
0
22
8
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
15
8
8
15
8
58
15
0
8
0
8
0
0
0
% P
% Gln:
8
0
0
0
8
8
8
0
0
0
8
0
0
0
8
% Q
% Arg:
43
0
8
8
43
8
8
0
8
22
8
15
36
0
8
% R
% Ser:
15
8
15
8
8
0
0
43
15
8
8
0
0
8
15
% S
% Thr:
8
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
8
8
8
0
0
0
0
8
36
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _