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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
10.91
Human Site:
S969
Identified Species:
18.46
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
S969
D
S
E
G
E
E
A
S
Q
E
S
S
S
E
K
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
S969
D
S
E
G
E
E
A
S
Q
E
S
S
S
E
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
Q664
Q
E
M
K
S
I
M
Q
R
D
L
N
R
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1093
R
S
R
I
S
S
P
S
S
S
S
S
S
D
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
P621
P
P
R
E
L
R
P
P
T
P
S
E
E
P
P
Chicken
Gallus gallus
Q5F3P8
2008
223067
D1019
D
S
E
G
E
E
G
D
E
T
S
G
K
E
E
Frog
Xenopus laevis
Q66J90
1938
216239
V982
D
S
E
G
E
E
E
V
E
S
E
G
D
D
G
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
S1018
D
S
S
D
D
E
A
S
S
S
S
S
S
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
E929
Y
E
A
I
D
C
V
E
K
A
R
T
S
E
E
Honey Bee
Apis mellifera
XP_395451
1406
159180
E740
A
S
S
E
S
S
S
E
E
M
S
C
S
E
S
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
S841
Y
N
N
Q
S
F
A
S
S
S
R
G
F
Y
R
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
K1186
K
T
V
I
Q
E
M
K
I
I
M
K
K
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
V414
I
P
Y
D
L
L
G
V
V
N
N
R
P
V
L
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
H647
D
Y
L
N
P
V
N
H
A
A
K
R
R
K
L
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
0
N.A.
40
N.A.
N.A.
6.6
53.3
40
53.3
N.A.
13.3
26.6
13.3
6.6
P-Site Similarity:
100
100
N.A.
26.6
N.A.
46.6
N.A.
N.A.
6.6
66.6
53.3
66.6
N.A.
40
40
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
29
0
8
15
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% C
% Asp:
43
0
0
15
15
0
0
8
0
8
0
0
8
22
0
% D
% Glu:
0
15
29
15
29
43
8
15
22
15
8
8
8
36
15
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
29
0
0
15
0
0
0
0
22
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
22
0
8
0
0
8
8
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
0
8
8
0
8
8
15
22
22
% K
% Leu:
0
0
8
0
15
8
0
0
0
0
8
0
0
0
22
% L
% Met:
0
0
8
0
0
0
15
0
0
8
8
0
0
0
8
% M
% Asn:
0
8
8
8
0
0
8
0
0
8
8
8
0
0
0
% N
% Pro:
8
15
0
0
8
0
15
8
0
8
0
0
8
8
8
% P
% Gln:
8
0
0
8
8
0
0
8
15
0
0
0
0
0
0
% Q
% Arg:
8
0
15
0
0
8
0
0
8
0
15
15
15
0
8
% R
% Ser:
0
50
15
0
29
15
8
36
22
29
50
29
43
0
15
% S
% Thr:
0
8
0
0
0
0
0
0
8
8
0
8
0
0
0
% T
% Val:
0
0
8
0
0
8
8
15
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
8
8
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _