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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
9.39
Human Site:
T1206
Identified Species:
15.9
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
T1206
A
P
R
G
V
E
R
T
I
R
N
L
P
L
D
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
T1206
A
P
R
G
V
E
R
T
I
R
N
L
P
L
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
H885
I
R
N
L
P
L
D
H
A
S
L
V
K
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1411
G
E
P
P
L
S
G
S
S
S
G
L
S
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
P842
P
A
P
R
E
R
K
P
G
R
P
K
R
S
P
Chicken
Gallus gallus
Q5F3P8
2008
223067
F1368
S
V
V
P
P
E
K
F
P
E
Q
L
M
V
T
Frog
Xenopus laevis
Q66J90
1938
216239
P1400
G
I
I
N
S
G
I
P
R
T
P
G
R
D
F
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
S1279
R
G
L
G
K
L
Q
S
T
D
T
V
P
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
I1156
D
E
T
R
K
T
A
I
S
Q
T
R
S
C
F
Honey Bee
Apis mellifera
XP_395451
1406
159180
I961
K
I
E
M
F
S
E
I
P
T
T
D
S
E
E
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
S1062
G
P
I
I
G
D
S
S
Y
L
P
Y
K
I
V
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
S1455
T
L
D
K
P
S
L
S
D
A
S
D
I
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
R635
L
D
H
T
S
L
K
R
K
K
L
S
N
G
I
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
A868
P
L
N
G
L
P
D
A
D
V
K
A
E
P
A
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
0
N.A.
13.3
N.A.
N.A.
6.6
13.3
0
13.3
N.A.
0
0
6.6
0
P-Site Similarity:
100
100
N.A.
6.6
N.A.
26.6
N.A.
N.A.
13.3
33.3
0
40
N.A.
6.6
6.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
0
0
8
8
8
8
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
8
8
0
0
8
15
0
15
8
0
15
0
8
15
% D
% Glu:
0
15
8
0
8
22
8
0
0
8
0
0
8
15
8
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
15
% F
% Gly:
22
8
0
29
8
8
8
0
8
0
8
8
0
8
0
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
15
15
8
0
0
8
15
15
0
0
0
8
8
8
% I
% Lys:
8
0
0
8
15
0
22
0
8
8
8
8
15
0
0
% K
% Leu:
8
15
8
8
15
22
8
0
0
8
15
29
0
22
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
15
8
0
0
0
0
0
0
15
0
8
0
0
% N
% Pro:
15
22
15
15
22
8
0
15
15
0
22
0
22
8
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% Q
% Arg:
8
8
15
15
0
8
15
8
8
22
0
8
15
0
0
% R
% Ser:
8
0
0
0
15
22
8
29
15
15
8
8
22
15
15
% S
% Thr:
8
0
8
8
0
8
0
15
8
15
22
0
0
0
15
% T
% Val:
0
8
8
0
15
0
0
0
0
8
0
15
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _