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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
18.79
Human Site:
T1475
Identified Species:
31.79
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
T1475
H
T
I
T
N
L
T
T
P
K
R
K
R
R
P
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
T1475
H
T
I
T
N
L
T
T
P
K
R
K
R
R
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
T1114
D
G
P
R
E
H
Q
T
G
S
A
R
S
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1748
H
P
S
T
S
L
S
S
A
K
K
K
K
R
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
E1071
T
T
G
C
A
R
S
E
G
Y
Y
K
I
D
K
Chicken
Gallus gallus
Q5F3P8
2008
223067
T1771
H
P
S
T
S
F
S
T
P
K
K
K
K
R
D
Frog
Xenopus laevis
Q66J90
1938
216239
S1701
H
P
P
T
S
V
Y
S
P
K
K
K
K
R
D
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
S1606
H
P
P
T
N
M
G
S
A
T
G
V
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
F1391
H
C
T
T
D
R
A
F
W
P
P
P
S
K
K
Honey Bee
Apis mellifera
XP_395451
1406
159180
H1190
R
E
K
A
K
H
K
H
H
Y
A
Q
S
I
Q
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
S1291
I
P
V
A
A
G
C
S
R
A
R
P
Y
E
K
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
A1719
L
T
P
S
I
L
T
A
C
P
D
P
P
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
T864
R
V
H
Q
P
L
N
T
V
N
I
H
N
E
R
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
A1097
H
H
I
K
V
K
K
A
R
E
E
R
E
K
N
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
6.6
N.A.
40
N.A.
N.A.
13.3
46.6
40
20
N.A.
13.3
0
6.6
26.6
P-Site Similarity:
100
100
N.A.
13.3
N.A.
73.3
N.A.
N.A.
20
73.3
73.3
46.6
N.A.
26.6
6.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
15
0
8
15
15
8
15
0
0
0
0
% A
% Cys:
0
8
0
8
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
0
0
0
8
0
0
8
15
% D
% Glu:
0
8
0
0
8
0
0
8
0
8
8
0
8
22
8
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
8
8
0
15
0
8
0
0
0
8
% G
% His:
58
8
8
0
0
15
0
8
8
0
0
8
0
0
0
% H
% Ile:
8
0
22
0
8
0
0
0
0
0
8
0
8
8
0
% I
% Lys:
0
0
8
8
8
8
15
0
0
36
22
43
29
22
29
% K
% Leu:
8
0
0
0
0
36
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
22
0
8
0
0
8
0
0
8
0
8
% N
% Pro:
0
36
29
0
8
0
0
0
29
15
8
22
8
0
22
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
0
8
0
8
8
% Q
% Arg:
15
0
0
8
0
15
0
0
15
0
22
15
15
36
8
% R
% Ser:
0
0
15
8
22
0
22
29
0
8
0
0
22
0
0
% S
% Thr:
8
29
8
50
0
0
22
36
0
8
0
0
0
0
0
% T
% Val:
0
8
8
0
8
8
0
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
15
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _