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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
7.27
Human Site:
T388
Identified Species:
12.31
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
T388
S
Y
P
P
R
R
A
T
R
E
E
P
P
G
A
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
T388
S
Y
P
P
R
R
A
T
R
E
E
P
P
G
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
R132
I
L
L
H
P
R
T
R
K
H
L
G
L
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
P396
S
P
Y
Q
T
P
A
P
P
F
P
P
P
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
T89
P
P
T
H
P
A
V
T
V
P
P
P
P
L
P
Chicken
Gallus gallus
Q5F3P8
2008
223067
K447
D
F
A
P
V
K
E
K
P
E
E
P
P
P
L
Frog
Xenopus laevis
Q66J90
1938
216239
R414
S
R
D
M
E
Y
R
R
T
G
P
P
T
S
D
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
Y433
P
V
Q
R
E
L
D
Y
R
R
P
P
Q
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
K390
Q
R
D
R
G
S
L
K
Y
C
S
R
Y
S
L
Honey Bee
Apis mellifera
XP_395451
1406
159180
V208
V
M
G
K
V
L
K
V
F
L
D
A
F
G
E
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
P309
I
K
E
E
S
P
P
P
P
P
P
P
P
V
A
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
D454
G
S
K
R
Y
D
E
D
R
G
S
K
R
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
S115
S
H
T
S
T
S
S
S
I
F
S
S
S
T
R
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
6.6
N.A.
26.6
N.A.
N.A.
20
33.3
13.3
13.3
N.A.
0
6.6
20
6.6
P-Site Similarity:
100
100
N.A.
13.3
N.A.
26.6
N.A.
N.A.
20
46.6
13.3
13.3
N.A.
0
13.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
22
0
0
0
0
8
0
15
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
15
0
0
8
8
8
0
0
8
0
0
0
15
% D
% Glu:
0
0
8
8
15
0
15
0
0
22
22
0
0
0
15
% E
% Phe:
0
8
0
0
0
0
0
0
8
15
0
0
8
8
0
% F
% Gly:
8
0
8
0
8
0
0
0
0
15
0
8
0
22
0
% G
% His:
0
8
0
15
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
15
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
8
8
0
8
8
15
8
0
0
8
0
0
0
% K
% Leu:
0
8
8
0
0
15
8
0
0
8
8
0
8
8
15
% L
% Met:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
15
15
22
15
15
8
15
22
15
36
58
43
15
15
% P
% Gln:
8
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
15
0
22
15
22
8
15
29
8
0
8
8
0
15
% R
% Ser:
36
8
0
8
8
15
8
8
0
0
22
8
8
15
0
% S
% Thr:
0
0
15
0
15
0
8
22
8
0
0
0
8
8
0
% T
% Val:
8
8
0
0
15
0
8
8
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
8
0
8
8
0
8
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _