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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
23.03
Human Site:
Y1447
Identified Species:
38.97
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
Y1447
M
S
Y
L
R
L
T
Y
E
R
L
L
Q
Q
T
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
Y1447
M
S
Y
L
R
L
T
Y
E
R
L
L
Q
Q
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
T1086
G
A
D
W
L
N
D
T
H
W
V
H
H
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
Y1720
I
R
F
L
C
V
T
Y
E
R
L
L
Q
Q
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
H1043
N
D
T
L
W
V
Y
H
P
S
T
S
F
S
T
Chicken
Gallus gallus
Q5F3P8
2008
223067
Y1743
I
K
F
M
C
I
T
Y
D
R
L
L
Q
Q
D
Frog
Xenopus laevis
Q66J90
1938
216239
Y1673
M
K
Y
M
C
I
T
Y
D
R
L
L
Q
Q
D
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
Y1578
I
R
Y
L
K
I
T
Y
D
K
M
L
Q
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
Y1363
I
N
F
I
K
M
S
Y
L
D
H
L
H
K
E
Honey Bee
Apis mellifera
XP_395451
1406
159180
D1162
P
A
K
R
R
K
R
D
E
L
R
L
H
T
S
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
P1263
D
P
L
L
R
L
N
P
I
R
S
K
K
G
L
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
H1691
K
A
E
K
K
K
A
H
S
T
T
P
R
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
K836
L
Q
P
G
S
S
F
K
A
E
G
F
R
K
I
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
G1069
Y
Y
V
P
N
P
T
G
C
A
R
T
E
G
V
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
0
N.A.
60
N.A.
N.A.
13.3
46.6
60
46.6
N.A.
13.3
20
26.6
0
P-Site Similarity:
100
100
N.A.
13.3
N.A.
80
N.A.
N.A.
26.6
80
80
86.6
N.A.
66.6
33.3
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
0
0
0
8
0
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
22
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
0
0
8
8
22
8
0
0
0
0
29
% D
% Glu:
0
0
8
0
0
0
0
0
29
8
0
0
8
0
8
% E
% Phe:
0
0
22
0
0
0
8
0
0
0
0
8
8
0
0
% F
% Gly:
8
0
0
8
0
0
0
8
0
0
8
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
15
8
0
8
8
22
0
0
% H
% Ile:
29
0
0
8
0
22
0
0
8
0
0
0
0
0
15
% I
% Lys:
8
15
8
8
22
15
0
8
0
8
0
8
8
15
0
% K
% Leu:
8
0
8
43
8
22
0
0
8
8
36
58
0
0
8
% L
% Met:
22
0
0
15
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
8
0
0
8
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
8
8
0
8
0
8
8
0
0
8
0
0
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
43
43
0
% Q
% Arg:
0
15
0
8
29
0
8
0
0
43
15
0
15
0
0
% R
% Ser:
0
15
0
0
8
8
8
0
8
8
8
8
0
15
8
% S
% Thr:
0
0
8
0
0
0
50
8
0
8
15
8
0
15
22
% T
% Val:
0
0
8
0
0
15
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
8
8
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
8
8
29
0
0
0
8
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _