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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
5.45
Human Site:
Y657
Identified Species:
9.23
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
Y657
P
P
P
P
P
H
I
Y
D
F
V
N
S
L
E
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
Y657
P
P
P
P
P
H
I
Y
D
F
V
N
S
L
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
A393
A
S
Y
P
P
R
R
A
T
R
E
E
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
A710
P
P
P
P
P
P
P
A
H
P
A
V
T
V
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
S350
V
D
D
D
D
E
E
S
E
R
D
R
D
G
G
Chicken
Gallus gallus
Q5F3P8
2008
223067
P725
T
V
P
P
P
P
L
P
A
P
P
G
V
P
P
Frog
Xenopus laevis
Q66J90
1938
216239
P677
P
P
L
P
P
P
P
P
P
T
H
P
S
V
T
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
M705
S
L
P
Q
L
L
Q
M
P
F
Q
M
Q
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
P655
Y
S
H
S
N
Q
N
P
F
Y
Y
H
A
S
G
Honey Bee
Apis mellifera
XP_395451
1406
159180
L469
D
R
M
S
L
S
P
L
S
S
G
D
E
K
I
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
P570
P
S
V
H
L
Q
T
P
Y
Q
H
V
Q
P
Q
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
S742
S
E
G
E
D
T
D
S
F
A
L
S
L
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
D143
S
V
L
R
Y
N
T
D
N
L
K
S
K
F
H
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
E376
G
M
H
G
R
R
I
E
A
N
Q
V
R
V
E
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
13.3
N.A.
33.3
N.A.
N.A.
0
20
33.3
13.3
N.A.
0
0
6.6
0
P-Site Similarity:
100
100
N.A.
13.3
N.A.
46.6
N.A.
N.A.
6.6
26.6
40
20
N.A.
20
6.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
15
15
8
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
15
0
8
8
15
0
8
8
8
8
0
% D
% Glu:
0
8
0
8
0
8
8
8
8
0
8
8
8
0
22
% E
% Phe:
0
0
0
0
0
0
0
0
15
22
0
0
0
8
0
% F
% Gly:
8
0
8
8
0
0
0
0
0
0
8
8
0
8
22
% G
% His:
0
0
15
8
0
15
0
0
8
0
15
8
0
0
8
% H
% Ile:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% K
% Leu:
0
8
15
0
22
8
8
8
0
8
8
0
8
15
0
% L
% Met:
0
8
8
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
8
8
0
8
8
0
15
0
0
0
% N
% Pro:
36
29
36
43
43
22
22
29
15
15
8
8
8
22
15
% P
% Gln:
0
0
0
8
0
15
8
0
0
8
15
0
15
0
15
% Q
% Arg:
0
8
0
8
8
15
8
0
0
15
0
8
8
0
0
% R
% Ser:
22
22
0
15
0
8
0
15
8
8
0
15
22
8
0
% S
% Thr:
8
0
0
0
0
8
15
0
8
8
0
0
8
8
15
% T
% Val:
8
15
8
0
0
0
0
0
0
0
15
22
8
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
8
0
0
15
8
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _