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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM6B
All Species:
14.24
Human Site:
S139
Identified Species:
31.33
UniProt:
O15054
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15054
NP_001073893
1679
180411
S139
S
A
L
R
Y
G
G
S
F
A
E
L
G
P
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110616
1677
180308
S139
S
A
L
R
Y
G
G
S
F
A
E
L
G
P
R
Dog
Lupus familis
XP_546599
1653
177377
S139
S
A
L
R
Y
G
G
S
L
A
E
L
G
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5NCY0
1641
176337
S139
R
A
L
R
Y
G
G
S
F
A
E
L
G
P
R
Rat
Rattus norvegicus
NP_001102299
1361
146305
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512545
1373
151321
T12
L
P
N
S
L
G
V
T
L
L
R
G
V
V
V
Chicken
Gallus gallus
XP_416762
1384
152840
A22
R
R
R
L
A
A
R
A
Q
A
G
G
E
A
V
Frog
Xenopus laevis
NP_001086774
1455
160368
E94
L
K
S
E
G
K
V
E
A
D
F
F
S
H
L
Zebra Danio
Brachydanio rerio
XP_684619
1964
216217
P146
P
A
L
Q
R
M
P
P
A
P
P
R
P
W
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723550
939
106399
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203582
1412
156309
S50
L
G
W
L
Y
H
S
S
D
Q
L
G
D
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
91.7
N.A.
90.1
74.6
N.A.
31.8
31.6
31
39.5
N.A.
27.6
N.A.
N.A.
29.6
Protein Similarity:
100
N.A.
98.4
93
N.A.
92.2
76.2
N.A.
44.3
44.7
45
51
N.A.
39.4
N.A.
N.A.
43.7
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
0
N.A.
6.6
6.6
0
13.3
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
0
N.A.
13.3
13.3
0
20
N.A.
0
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
0
0
10
10
0
10
19
46
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
10
0
0
10
0
10
% D
% Glu:
0
0
0
10
0
0
0
10
0
0
37
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
28
0
10
10
0
0
0
% F
% Gly:
0
10
0
0
10
46
37
0
0
0
10
28
37
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
28
0
46
19
10
0
0
0
19
10
10
37
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
0
0
0
10
10
0
10
10
0
10
37
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
10
0
0
0
0
0
% Q
% Arg:
19
10
10
37
10
0
10
0
0
0
10
10
0
0
37
% R
% Ser:
28
0
10
10
0
0
10
46
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
19
0
0
0
0
0
10
10
19
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
46
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _