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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM6B
All Species:
6.97
Human Site:
S990
Identified Species:
15.33
UniProt:
O15054
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15054
NP_001073893
1679
180411
S990
H
R
R
A
C
K
D
S
V
G
R
R
P
R
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110616
1677
180308
S988
H
R
R
A
C
K
D
S
V
G
R
R
P
R
E
Dog
Lupus familis
XP_546599
1653
177377
Q986
K
R
R
Q
K
E
H
Q
K
E
H
Q
K
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q5NCY0
1641
176337
E980
S
G
K
R
R
Q
K
E
H
R
R
H
R
R
A
Rat
Rattus norvegicus
NP_001102299
1361
146305
E700
S
G
K
R
R
Q
K
E
H
R
R
H
R
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512545
1373
151321
P712
S
R
H
S
G
E
T
P
N
S
T
A
G
V
E
Chicken
Gallus gallus
XP_416762
1384
152840
N723
R
H
S
G
E
T
P
N
S
T
A
G
V
E
G
Frog
Xenopus laevis
NP_001086774
1455
160368
S794
H
S
E
G
T
P
N
S
T
A
G
V
E
G
L
Zebra Danio
Brachydanio rerio
XP_684619
1964
216217
S1093
L
H
Q
T
G
V
N
S
M
F
K
N
L
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723550
939
106399
R278
I
S
L
E
M
N
S
R
Q
Q
Q
T
A
Q
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203582
1412
156309
Q751
N
Q
F
Q
A
S
F
Q
S
A
L
A
E
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
91.7
N.A.
90.1
74.6
N.A.
31.8
31.6
31
39.5
N.A.
27.6
N.A.
N.A.
29.6
Protein Similarity:
100
N.A.
98.4
93
N.A.
92.2
76.2
N.A.
44.3
44.7
45
51
N.A.
39.4
N.A.
N.A.
43.7
P-Site Identity:
100
N.A.
100
13.3
N.A.
13.3
13.3
N.A.
13.3
0
13.3
6.6
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
100
26.6
N.A.
26.6
26.6
N.A.
26.6
6.6
20
33.3
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
10
0
0
0
0
19
10
19
10
10
10
% A
% Cys:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
10
10
19
0
19
0
10
0
0
19
19
28
% E
% Phe:
0
0
10
0
0
0
10
0
0
10
0
0
0
0
0
% F
% Gly:
0
19
0
19
19
0
0
0
0
19
10
10
10
10
10
% G
% His:
28
19
10
0
0
0
10
0
19
0
10
19
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
19
0
10
19
19
0
10
0
10
0
10
10
0
% K
% Leu:
10
0
10
0
0
0
0
0
0
0
10
0
10
0
10
% L
% Met:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
10
19
10
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
10
0
0
0
0
19
0
0
% P
% Gln:
0
10
10
19
0
19
0
19
10
10
10
10
0
10
10
% Q
% Arg:
10
37
28
19
19
0
0
10
0
19
37
19
19
37
0
% R
% Ser:
28
19
10
10
0
10
10
37
19
10
0
0
0
0
10
% S
% Thr:
0
0
0
10
10
10
10
0
10
10
10
10
0
0
10
% T
% Val:
0
0
0
0
0
10
0
0
19
0
0
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _