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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM6B
All Species:
8.18
Human Site:
T127
Identified Species:
18
UniProt:
O15054
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15054
NP_001073893
1679
180411
T127
E
H
D
S
E
E
A
T
R
C
Y
H
S
A
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110616
1677
180308
T127
E
H
D
S
E
E
A
T
R
C
Y
H
S
A
L
Dog
Lupus familis
XP_546599
1653
177377
I127
E
H
D
S
E
E
A
I
R
C
Y
H
S
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5NCY0
1641
176337
V127
E
H
D
S
E
E
A
V
C
C
Y
H
R
A
L
Rat
Rattus norvegicus
NP_001102299
1361
146305
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512545
1373
151321
Chicken
Gallus gallus
XP_416762
1384
152840
R10
D
V
S
Q
Q
R
S
R
A
A
P
R
R
R
R
Frog
Xenopus laevis
NP_001086774
1455
160368
Y82
L
L
K
A
V
R
C
Y
E
A
L
I
L
K
S
Zebra Danio
Brachydanio rerio
XP_684619
1964
216217
S134
R
G
D
K
Q
D
Q
S
Q
A
L
M
P
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723550
939
106399
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203582
1412
156309
T38
L
P
E
G
L
K
A
T
T
F
R
Q
L
G
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
91.7
N.A.
90.1
74.6
N.A.
31.8
31.6
31
39.5
N.A.
27.6
N.A.
N.A.
29.6
Protein Similarity:
100
N.A.
98.4
93
N.A.
92.2
76.2
N.A.
44.3
44.7
45
51
N.A.
39.4
N.A.
N.A.
43.7
P-Site Identity:
100
N.A.
100
93.3
N.A.
80
0
N.A.
0
0
0
20
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
80
0
N.A.
0
20
6.6
46.6
N.A.
0
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
46
0
10
28
0
0
0
46
0
% A
% Cys:
0
0
0
0
0
0
10
0
10
37
0
0
0
0
0
% C
% Asp:
10
0
46
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
37
0
10
0
37
37
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
37
0
0
0
0
0
0
0
0
0
37
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% I
% Lys:
0
0
10
10
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
19
10
0
0
10
0
0
0
0
0
19
0
19
0
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
10
19
0
10
0
10
0
0
10
0
0
0
% Q
% Arg:
10
0
0
0
0
19
0
10
28
0
10
10
19
10
10
% R
% Ser:
0
0
10
37
0
0
10
10
0
0
0
0
28
0
10
% S
% Thr:
0
0
0
0
0
0
0
28
10
0
0
0
0
0
0
% T
% Val:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
37
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _