Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDM6B All Species: 7.58
Human Site: T542 Identified Species: 16.67
UniProt: O15054 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15054 NP_001073893 1679 180411 T542 Q D S H T P P T P P T P T T S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110616 1677 180308 T541 Q D S H T P P T P P A P T T S
Dog Lupus familis XP_546599 1653 177377 P549 G T Q D S H T P P T P P A T S
Cat Felis silvestris
Mouse Mus musculus Q5NCY0 1641 176337 P547 G T Q D S H N P P I P P T T T
Rat Rattus norvegicus NP_001102299 1361 146305 S314 I D P L P R P S S P T L S S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512545 1373 151321 A326 Q L D H G H A A A W M D L G T
Chicken Gallus gallus XP_416762 1384 152840 A337 L D H G H A A A W M D L G T L
Frog Xenopus laevis NP_001086774 1455 160368 Q408 A Q L C N L P Q G S L Q N K T
Zebra Danio Brachydanio rerio XP_684619 1964 216217 T556 Q I Q Q S T L T H T G Q S R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_723550 939 106399
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203582 1412 156309 Q365 Q P S V N Q Q Q Q Q Q Q Q V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98 91.7 N.A. 90.1 74.6 N.A. 31.8 31.6 31 39.5 N.A. 27.6 N.A. N.A. 29.6
Protein Similarity: 100 N.A. 98.4 93 N.A. 92.2 76.2 N.A. 44.3 44.7 45 51 N.A. 39.4 N.A. N.A. 43.7
P-Site Identity: 100 N.A. 93.3 26.6 N.A. 26.6 26.6 N.A. 13.3 13.3 6.6 13.3 N.A. 0 N.A. N.A. 20
P-Site Similarity: 100 N.A. 93.3 33.3 N.A. 40 46.6 N.A. 20 13.3 13.3 26.6 N.A. 0 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 19 19 10 0 10 0 10 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 37 10 19 0 0 0 0 0 0 10 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 19 0 0 10 10 0 0 0 10 0 10 0 10 10 0 % G
% His: 0 0 10 28 10 28 0 0 10 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 10 10 10 10 0 10 10 0 0 0 10 19 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % M
% Asn: 0 0 0 0 19 0 10 0 0 0 0 0 10 0 0 % N
% Pro: 0 10 10 0 10 19 37 19 37 28 19 37 0 0 10 % P
% Gln: 46 10 28 10 0 10 10 19 10 10 10 28 10 0 10 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 28 0 28 0 0 10 10 10 0 0 19 10 37 % S
% Thr: 0 19 0 0 19 10 10 28 0 19 19 0 28 46 28 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _