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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM6B
All Species:
4.55
Human Site:
Y1186
Identified Species:
10
UniProt:
O15054
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15054
NP_001073893
1679
180411
Y1186
N
P
P
T
P
S
I
Y
L
E
S
K
R
D
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110616
1677
180308
Y1184
N
P
P
T
P
S
I
Y
L
E
S
K
R
D
A
Dog
Lupus familis
XP_546599
1653
177377
Q1174
E
S
Y
L
S
P
A
Q
S
V
K
P
K
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5NCY0
1641
176337
K1167
P
A
Q
S
V
K
P
K
I
N
T
E
E
K
L
Rat
Rattus norvegicus
NP_001102299
1361
146305
K887
P
A
Q
S
V
K
P
K
I
N
T
E
E
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512545
1373
151321
P899
P
P
R
P
P
P
P
P
Y
P
P
L
P
K
D
Chicken
Gallus gallus
XP_416762
1384
152840
P910
P
P
R
P
P
P
P
P
Y
P
P
L
P
K
D
Frog
Xenopus laevis
NP_001086774
1455
160368
P981
P
P
R
P
S
P
P
P
Y
P
P
L
P
T
D
Zebra Danio
Brachydanio rerio
XP_684619
1964
216217
Q1333
H
K
E
K
K
S
R
Q
V
L
G
N
L
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723550
939
106399
Q465
P
Q
K
L
T
R
D
Q
L
L
P
P
T
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203582
1412
156309
L938
G
L
F
S
T
K
T
L
V
E
T
H
G
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
91.7
N.A.
90.1
74.6
N.A.
31.8
31.6
31
39.5
N.A.
27.6
N.A.
N.A.
29.6
Protein Similarity:
100
N.A.
98.4
93
N.A.
92.2
76.2
N.A.
44.3
44.7
45
51
N.A.
39.4
N.A.
N.A.
43.7
P-Site Identity:
100
N.A.
100
0
N.A.
0
0
N.A.
13.3
13.3
6.6
13.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
6.6
N.A.
26.6
26.6
N.A.
13.3
13.3
6.6
26.6
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
0
10
0
0
0
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
37
28
% D
% Glu:
10
0
10
0
0
0
0
0
0
28
0
19
19
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
0
0
0
0
19
0
19
0
0
0
0
10
0
% I
% Lys:
0
10
10
10
10
28
0
19
0
0
10
19
10
37
0
% K
% Leu:
0
10
0
19
0
0
0
10
28
19
0
28
10
0
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
0
0
0
0
0
19
0
10
0
0
10
% N
% Pro:
55
46
19
28
37
37
46
28
0
28
37
19
28
10
0
% P
% Gln:
0
10
19
0
0
0
0
28
0
0
0
0
0
0
0
% Q
% Arg:
0
0
28
0
0
10
10
0
0
0
0
0
19
0
0
% R
% Ser:
0
10
0
28
19
28
0
0
10
0
19
0
0
0
10
% S
% Thr:
0
0
0
19
19
0
10
0
0
0
28
0
10
10
0
% T
% Val:
0
0
0
0
19
0
0
0
19
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
19
28
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _