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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PER2 All Species: 4.55
Human Site: T80 Identified Species: 11.11
UniProt: O15055 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15055 NP_073728.1 1255 136579 T80 D A R Q S P D T F S L M M A K
Chimpanzee Pan troglodytes XP_001154675 1255 136529 T80 D A R Q S P D T F S L M M A K
Rhesus Macaque Macaca mulatta XP_001086845 1248 135700 A80 D A H Q S P D A F S L M I T K
Dog Lupus familis XP_543306 1265 136160 A80 G A F G L M M A K S E H S T S
Cat Felis silvestris
Mouse Mus musculus O54943 1257 135863 M82 P D D A F R L M M T E A E H N
Rat Rattus norvegicus Q9Z301 1257 136010 M82 P D D T F R L M M T E A E H N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506324 1322 146225 A88 H K S S H S N A F T L M I A N
Chicken Gallus gallus Q8QGQ8 1344 147924 A130 H K S S S S N A F S L M I A N
Frog Xenopus laevis NP_001079172 1142 123501 E31 M E G T Q Q D E T D T N S H G
Zebra Danio Brachydanio rerio NP_878277 1404 152881 F145 P P S S T N A F S L L S A S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.1 75 N.A. 79.3 78.3 N.A. 61.6 57.3 39.8 47.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 95.6 81.9 N.A. 85.5 85.3 N.A. 73.2 69.4 54.3 62.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 73.3 13.3 N.A. 0 0 N.A. 26.6 40 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 80 13.3 N.A. 6.6 6.6 N.A. 46.6 53.3 6.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 0 10 0 0 10 40 0 0 0 20 10 40 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 30 20 20 0 0 0 40 0 0 10 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 10 0 0 30 0 20 0 0 % E
% Phe: 0 0 10 0 20 0 0 10 50 0 0 0 0 0 0 % F
% Gly: 10 0 10 10 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 20 0 10 0 10 0 0 0 0 0 0 10 0 30 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 30 0 0 % I
% Lys: 0 20 0 0 0 0 0 0 10 0 0 0 0 0 30 % K
% Leu: 0 0 0 0 10 0 20 0 0 10 60 0 0 0 0 % L
% Met: 10 0 0 0 0 10 10 20 20 0 0 50 20 0 0 % M
% Asn: 0 0 0 0 0 10 20 0 0 0 0 10 0 0 40 % N
% Pro: 30 10 0 0 0 30 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 30 10 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 20 0 0 20 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 30 30 40 20 0 0 10 50 0 10 20 10 20 % S
% Thr: 0 0 0 20 10 0 0 20 10 30 10 0 0 20 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _