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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYNM All Species: 13.64
Human Site: S527 Identified Species: 42.86
UniProt: O15061 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15061 NP_056101.5 1565 172768 S527 P E E K M F D S K E K A S E E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001108469 1760 194258 S722 P E E K M F D S K E K A S E E
Dog Lupus familis XP_536177 1449 161251 E428 R L C A Q E A E A L R R E A L
Cat Felis silvestris
Mouse Mus musculus Q70IV5 1561 173191 S528 P E E K M F D S K E K A S E E
Rat Rattus norvegicus NP_001128330 1557 172861 S527 P E E K M F D S K E K A S E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508510 1495 168262 L458 R W E E L T K L D K E T R E R
Chicken Gallus gallus NP_990140 1604 182170 E583 E Q K K Y V R E E V I S Q K V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038340 1073 122118 Q94 R N E L Q A L Q A M R S D E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 83.5 59.4 N.A. 69.2 68.7 N.A. 40 38.4 N.A. 23.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 85.5 68 N.A. 78.9 78.3 N.A. 56.7 55.6 N.A. 40.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 0 N.A. 100 100 N.A. 13.3 6.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 6.6 N.A. 100 100 N.A. 40 40 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 0 13 13 0 25 0 0 50 0 13 13 % A
% Cys: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 50 0 13 0 0 0 13 0 0 % D
% Glu: 13 50 75 13 0 13 0 25 13 50 13 0 13 75 50 % E
% Phe: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % I
% Lys: 0 0 13 63 0 0 13 0 50 13 50 0 0 13 0 % K
% Leu: 0 13 0 13 13 0 13 13 0 13 0 0 0 0 13 % L
% Met: 0 0 0 0 50 0 0 0 0 13 0 0 0 0 0 % M
% Asn: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 13 0 0 25 0 0 13 0 0 0 0 13 0 0 % Q
% Arg: 38 0 0 0 0 0 13 0 0 0 25 13 13 0 13 % R
% Ser: 0 0 0 0 0 0 0 50 0 0 0 25 50 0 0 % S
% Thr: 0 0 0 0 0 13 0 0 0 0 0 13 0 0 0 % T
% Val: 0 0 0 0 0 13 0 0 0 13 0 0 0 0 13 % V
% Trp: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _