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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYNM
All Species:
13.64
Human Site:
S527
Identified Species:
42.86
UniProt:
O15061
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15061
NP_056101.5
1565
172768
S527
P
E
E
K
M
F
D
S
K
E
K
A
S
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108469
1760
194258
S722
P
E
E
K
M
F
D
S
K
E
K
A
S
E
E
Dog
Lupus familis
XP_536177
1449
161251
E428
R
L
C
A
Q
E
A
E
A
L
R
R
E
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q70IV5
1561
173191
S528
P
E
E
K
M
F
D
S
K
E
K
A
S
E
E
Rat
Rattus norvegicus
NP_001128330
1557
172861
S527
P
E
E
K
M
F
D
S
K
E
K
A
S
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508510
1495
168262
L458
R
W
E
E
L
T
K
L
D
K
E
T
R
E
R
Chicken
Gallus gallus
NP_990140
1604
182170
E583
E
Q
K
K
Y
V
R
E
E
V
I
S
Q
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038340
1073
122118
Q94
R
N
E
L
Q
A
L
Q
A
M
R
S
D
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.5
59.4
N.A.
69.2
68.7
N.A.
40
38.4
N.A.
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
85.5
68
N.A.
78.9
78.3
N.A.
56.7
55.6
N.A.
40.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
0
N.A.
100
100
N.A.
13.3
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
6.6
N.A.
100
100
N.A.
40
40
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
13
13
0
25
0
0
50
0
13
13
% A
% Cys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
0
13
0
0
0
13
0
0
% D
% Glu:
13
50
75
13
0
13
0
25
13
50
13
0
13
75
50
% E
% Phe:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% I
% Lys:
0
0
13
63
0
0
13
0
50
13
50
0
0
13
0
% K
% Leu:
0
13
0
13
13
0
13
13
0
13
0
0
0
0
13
% L
% Met:
0
0
0
0
50
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
13
0
0
25
0
0
13
0
0
0
0
13
0
0
% Q
% Arg:
38
0
0
0
0
0
13
0
0
0
25
13
13
0
13
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
25
50
0
0
% S
% Thr:
0
0
0
0
0
13
0
0
0
0
0
13
0
0
0
% T
% Val:
0
0
0
0
0
13
0
0
0
13
0
0
0
0
13
% V
% Trp:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _