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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFAS
All Species:
20.91
Human Site:
S260
Identified Species:
38.33
UniProt:
O15067
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15067
NP_036525
1338
144724
S260
S
I
M
S
T
Q
E
S
S
N
P
N
N
V
L
Chimpanzee
Pan troglodytes
XP_511854
1397
150781
S319
S
I
M
S
T
Q
E
S
S
N
P
N
N
V
L
Rhesus Macaque
Macaca mulatta
XP_001112405
1335
144369
S260
S
I
M
S
T
Q
E
S
S
N
P
N
N
V
L
Dog
Lupus familis
XP_850167
1368
147436
S260
S
I
M
S
T
Q
A
S
S
N
P
N
N
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUR0
1337
144611
S260
S
I
M
S
T
Q
A
S
S
N
P
N
N
V
L
Rat
Rattus norvegicus
NP_001099261
1271
136879
H240
V
V
F
T
A
E
T
H
N
F
P
T
G
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038667
1314
142462
H256
L
I
M
G
T
Q
Q
H
S
N
Q
N
N
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35421
1354
148067
H265
M
I
M
D
T
Q
A
H
T
N
P
N
N
T
I
Honey Bee
Apis mellifera
XP_625036
1243
138433
F236
N
T
N
N
T
I
K
F
S
D
N
S
S
A
I
Nematode Worm
Caenorhab. elegans
Q19311
1343
148611
S251
T
I
R
E
T
L
D
S
S
N
D
N
S
L
I
Sea Urchin
Strong. purpuratus
XP_781955
1205
129101
E239
S
N
M
A
R
P
L
E
V
A
V
E
A
S
N
Poplar Tree
Populus trichocarpa
XP_002315209
1377
150616
A314
I
V
K
S
T
L
Q
A
N
P
N
N
S
V
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8D3
1387
151761
A325
I
V
K
S
T
W
E
A
N
R
N
N
S
V
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
97.1
87.5
N.A.
88.5
84
N.A.
N.A.
N.A.
N.A.
63.2
N.A.
50.5
50.1
47.5
52.4
Protein Similarity:
100
95.2
98
91.6
N.A.
92.8
88.6
N.A.
N.A.
N.A.
N.A.
75.1
N.A.
66
66.2
64.1
65.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
N.A.
N.A.
N.A.
60
N.A.
53.3
13.3
40
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
40
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
66.6
60
73.3
20
Percent
Protein Identity:
50.3
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
65.2
N.A.
N.A.
65.3
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
24
16
0
8
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
8
8
0
0
0
0
% D
% Glu:
0
0
0
8
0
8
31
8
0
0
0
8
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% H
% Ile:
16
62
0
0
0
8
0
0
0
0
0
0
0
0
47
% I
% Lys:
0
0
16
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
16
8
0
0
0
0
0
0
8
39
% L
% Met:
8
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
8
0
0
0
0
24
62
24
77
54
0
8
% N
% Pro:
0
0
0
0
0
8
0
0
0
8
54
0
0
0
0
% P
% Gln:
0
0
0
0
0
54
16
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
47
0
0
54
0
0
0
47
62
0
0
8
31
8
0
% S
% Thr:
8
8
0
8
85
0
8
0
8
0
0
8
0
8
0
% T
% Val:
8
24
0
0
0
0
0
0
8
0
8
0
0
70
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _