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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFAS
All Species:
14.55
Human Site:
S439
Identified Species:
26.67
UniProt:
O15067
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15067
NP_036525
1338
144724
S439
S
M
E
A
D
H
I
S
K
E
A
P
E
P
G
Chimpanzee
Pan troglodytes
XP_511854
1397
150781
S498
S
M
E
A
D
H
I
S
K
E
A
P
E
P
G
Rhesus Macaque
Macaca mulatta
XP_001112405
1335
144369
S439
S
M
E
A
D
H
I
S
K
E
A
P
E
P
G
Dog
Lupus familis
XP_850167
1368
147436
R439
S
M
E
A
E
H
V
R
K
E
P
P
E
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUR0
1337
144611
G439
S
M
E
A
K
H
V
G
K
K
P
P
E
P
G
Rat
Rattus norvegicus
NP_001099261
1271
136879
G416
D
F
G
A
V
Q
R
G
D
P
E
M
E
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038667
1314
142462
R435
S
I
E
D
P
H
V
R
K
D
Q
A
E
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35421
1354
148067
E446
T
M
P
A
T
M
R
E
K
L
P
P
A
R
G
Honey Bee
Apis mellifera
XP_625036
1243
138433
L409
A
N
M
S
Q
K
V
L
P
Q
K
G
M
E
V
Nematode Worm
Caenorhab. elegans
Q19311
1343
148611
R431
A
I
D
K
D
E
V
R
K
E
P
C
A
P
H
Sea Urchin
Strong. purpuratus
XP_781955
1205
129101
W414
T
L
T
T
L
E
L
W
G
A
E
Y
Q
E
S
Poplar Tree
Populus trichocarpa
XP_002315209
1377
150616
T493
Q
I
D
H
T
H
I
T
K
G
E
P
D
I
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8D3
1387
151761
T504
Q
I
D
H
T
H
I
T
K
G
E
P
E
V
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
97.1
87.5
N.A.
88.5
84
N.A.
N.A.
N.A.
N.A.
63.2
N.A.
50.5
50.1
47.5
52.4
Protein Similarity:
100
95.2
98
91.6
N.A.
92.8
88.6
N.A.
N.A.
N.A.
N.A.
75.1
N.A.
66
66.2
64.1
65.4
P-Site Identity:
100
100
100
73.3
N.A.
66.6
13.3
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
33.3
0
26.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
80
13.3
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
40
26.6
53.3
26.6
Percent
Protein Identity:
50.3
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
65.2
N.A.
N.A.
65.3
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
54
0
0
0
0
0
8
24
8
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
0
24
8
31
0
0
0
8
8
0
0
8
0
0
% D
% Glu:
0
0
47
0
8
16
0
8
0
39
31
0
62
16
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
16
8
16
0
8
0
0
70
% G
% His:
0
0
0
16
0
62
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
31
0
0
0
0
39
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
8
8
8
0
0
77
8
8
0
0
0
8
% K
% Leu:
0
8
0
0
8
0
8
8
0
8
0
0
0
0
0
% L
% Met:
0
47
8
0
0
8
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
0
0
0
8
8
31
62
0
54
0
% P
% Gln:
16
0
0
0
8
8
0
0
0
8
8
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
16
24
0
0
0
0
0
8
0
% R
% Ser:
47
0
0
8
0
0
0
24
0
0
0
0
0
0
8
% S
% Thr:
16
0
8
8
24
0
0
16
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
39
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _