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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFAS
All Species:
12.12
Human Site:
S569
Identified Species:
22.22
UniProt:
O15067
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15067
NP_036525
1338
144724
S569
S
N
A
L
L
L
R
S
P
N
R
D
F
L
T
Chimpanzee
Pan troglodytes
XP_511854
1397
150781
S628
S
N
A
L
L
L
R
S
P
D
R
D
F
L
T
Rhesus Macaque
Macaca mulatta
XP_001112405
1335
144369
S569
S
N
A
L
L
L
R
S
P
D
R
N
F
L
T
Dog
Lupus familis
XP_850167
1368
147436
P569
S
N
A
L
L
L
R
P
L
D
R
D
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUR0
1337
144611
P569
S
N
A
L
L
L
R
P
S
D
R
D
F
L
S
Rat
Rattus norvegicus
NP_001099261
1271
136879
I527
T
I
T
G
D
K
R
I
V
L
V
D
D
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038667
1314
142462
P565
S
N
A
L
L
L
R
P
S
D
R
S
F
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35421
1354
148067
A578
N
N
A
I
L
C
N
A
D
Q
R
E
L
L
E
Honey Bee
Apis mellifera
XP_625036
1243
138433
S531
N
D
A
I
L
C
K
S
E
N
T
N
L
L
K
Nematode Worm
Caenorhab. elegans
Q19311
1343
148611
A561
N
D
A
A
L
V
D
A
S
L
L
D
A
L
Q
Sea Urchin
Strong. purpuratus
XP_781955
1205
129101
L518
T
V
R
N
L
S
P
L
V
L
P
D
G
L
T
Poplar Tree
Populus trichocarpa
XP_002315209
1377
150616
A622
Q
D
A
I
L
V
K
A
E
S
R
D
L
L
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8D3
1387
151761
A633
Q
D
A
I
L
V
K
A
E
S
R
E
I
L
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
97.1
87.5
N.A.
88.5
84
N.A.
N.A.
N.A.
N.A.
63.2
N.A.
50.5
50.1
47.5
52.4
Protein Similarity:
100
95.2
98
91.6
N.A.
92.8
88.6
N.A.
N.A.
N.A.
N.A.
75.1
N.A.
66
66.2
64.1
65.4
P-Site Identity:
100
93.3
86.6
73.3
N.A.
73.3
13.3
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
33.3
33.3
26.6
26.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
20
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
60
66.6
53.3
33.3
Percent
Protein Identity:
50.3
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
65.2
N.A.
N.A.
65.3
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
85
8
0
0
0
31
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
31
0
0
8
0
8
0
8
39
0
62
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
24
0
0
16
0
0
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
31
0
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
8
24
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
47
93
47
0
8
8
24
8
0
24
93
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
24
54
0
8
0
0
8
0
0
16
0
16
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
24
24
0
8
0
0
0
0
% P
% Gln:
16
0
0
0
0
0
0
0
0
8
0
0
0
0
24
% Q
% Arg:
0
0
8
0
0
0
54
0
0
0
70
0
0
8
0
% R
% Ser:
47
0
0
0
0
8
0
31
24
16
0
8
0
0
16
% S
% Thr:
16
0
8
0
0
0
0
0
0
0
8
0
0
0
31
% T
% Val:
0
8
0
0
0
24
0
0
16
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _