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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFAS
All Species:
14.24
Human Site:
S77
Identified Species:
26.11
UniProt:
O15067
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15067
NP_036525
1338
144724
S77
L
D
D
V
A
R
E
S
W
L
L
P
G
S
N
Chimpanzee
Pan troglodytes
XP_511854
1397
150781
S136
L
D
D
V
A
R
E
S
W
L
L
P
G
S
N
Rhesus Macaque
Macaca mulatta
XP_001112405
1335
144369
S77
L
D
D
V
A
Q
E
S
W
L
L
S
G
S
S
Dog
Lupus familis
XP_850167
1368
147436
S77
L
G
D
V
A
Q
E
S
W
L
H
P
D
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUR0
1337
144611
P77
R
D
D
V
A
Q
E
P
W
L
V
P
G
S
N
Rat
Rattus norvegicus
NP_001099261
1271
136879
M78
L
A
A
L
H
D
R
M
T
E
Q
H
Y
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038667
1314
142462
A74
L
E
E
P
T
L
K
A
E
H
G
A
R
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35421
1354
148067
A77
Q
S
L
S
R
Q
P
A
L
Q
S
T
G
S
S
Honey Bee
Apis mellifera
XP_625036
1243
138433
T74
H
N
L
K
S
S
S
T
F
N
E
K
L
N
N
Nematode Worm
Caenorhab. elegans
Q19311
1343
148611
E74
F
E
T
S
V
W
K
E
S
Q
L
H
P
E
H
Sea Urchin
Strong. purpuratus
XP_781955
1205
129101
L77
K
V
S
S
S
S
V
L
D
A
K
K
T
E
D
Poplar Tree
Populus trichocarpa
XP_002315209
1377
150616
K131
G
T
E
S
F
L
E
K
K
T
K
E
G
V
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8D3
1387
151761
R142
G
T
D
S
F
L
E
R
K
K
Q
E
G
L
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
97.1
87.5
N.A.
88.5
84
N.A.
N.A.
N.A.
N.A.
63.2
N.A.
50.5
50.1
47.5
52.4
Protein Similarity:
100
95.2
98
91.6
N.A.
92.8
88.6
N.A.
N.A.
N.A.
N.A.
75.1
N.A.
66
66.2
64.1
65.4
P-Site Identity:
100
100
80
66.6
N.A.
73.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
13.3
6.6
6.6
0
P-Site Similarity:
100
100
93.3
80
N.A.
86.6
20
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
33.3
40
26.6
13.3
Percent
Protein Identity:
50.3
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
65.2
N.A.
N.A.
65.3
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
39
0
0
16
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
31
47
0
0
8
0
0
8
0
0
0
8
0
16
% D
% Glu:
0
16
16
0
0
0
54
8
8
8
8
16
0
16
0
% E
% Phe:
8
0
0
0
16
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
16
8
0
0
0
0
0
0
0
0
8
0
54
0
0
% G
% His:
8
0
0
0
8
0
0
0
0
8
8
16
0
0
16
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
16
8
16
8
16
16
0
0
0
% K
% Leu:
47
0
16
8
0
24
0
8
8
39
31
0
8
16
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
8
0
0
0
8
39
% N
% Pro:
0
0
0
8
0
0
8
8
0
0
0
31
8
8
0
% P
% Gln:
8
0
0
0
0
31
0
0
0
16
16
0
0
0
0
% Q
% Arg:
8
0
0
0
8
16
8
8
0
0
0
0
8
0
0
% R
% Ser:
0
8
8
39
16
16
8
31
8
0
8
8
0
47
24
% S
% Thr:
0
16
8
0
8
0
0
8
8
8
0
8
8
0
0
% T
% Val:
0
8
0
39
8
0
8
0
0
0
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
8
0
0
39
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _