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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFAS
All Species:
6.97
Human Site:
T57
Identified Species:
12.78
UniProt:
O15067
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15067
NP_036525
1338
144724
T57
A
L
P
S
A
E
E
T
K
K
L
M
W
L
F
Chimpanzee
Pan troglodytes
XP_511854
1397
150781
T116
A
L
P
S
A
E
E
T
K
K
L
M
W
L
F
Rhesus Macaque
Macaca mulatta
XP_001112405
1335
144369
M57
A
L
P
S
A
E
E
M
K
K
L
M
W
L
F
Dog
Lupus familis
XP_850167
1368
147436
M57
S
P
P
N
A
E
E
M
K
K
L
M
W
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUR0
1337
144611
M57
T
L
P
W
A
E
E
M
K
K
L
M
W
L
F
Rat
Rattus norvegicus
NP_001099261
1271
136879
T63
L
S
F
A
K
Q
P
T
A
E
M
E
A
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038667
1314
142462
S59
D
I
L
R
W
L
F
S
P
P
Y
S
V
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35421
1354
148067
L57
H
S
L
A
L
D
E
L
L
V
W
L
V
K
Q
Honey Bee
Apis mellifera
XP_625036
1243
138433
I59
E
L
K
I
L
K
W
I
L
S
S
P
L
E
S
Nematode Worm
Caenorhab. elegans
Q19311
1343
148611
E56
E
L
I
S
S
N
W
E
K
L
V
T
L
L
S
Sea Urchin
Strong. purpuratus
XP_781955
1205
129101
K57
L
T
A
D
E
L
K
K
L
L
F
I
L
G
T
Poplar Tree
Populus trichocarpa
XP_002315209
1377
150616
C109
V
S
S
Q
K
L
G
C
L
R
W
L
L
Q
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8D3
1387
151761
V120
L
K
D
E
K
L
S
V
L
K
W
I
L
Q
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
97.1
87.5
N.A.
88.5
84
N.A.
N.A.
N.A.
N.A.
63.2
N.A.
50.5
50.1
47.5
52.4
Protein Similarity:
100
95.2
98
91.6
N.A.
92.8
88.6
N.A.
N.A.
N.A.
N.A.
75.1
N.A.
66
66.2
64.1
65.4
P-Site Identity:
100
100
93.3
73.3
N.A.
80
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
6.6
6.6
26.6
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
40
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
26.6
13.3
40
13.3
Percent
Protein Identity:
50.3
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
65.2
N.A.
N.A.
65.3
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
8
16
39
0
0
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
0
0
8
8
39
47
8
0
8
0
8
0
8
16
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
39
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
8
0
0
0
8
0
0
0
16
0
8
0
% I
% Lys:
0
8
8
0
24
8
8
8
47
47
0
0
0
8
0
% K
% Leu:
24
47
16
0
16
31
0
8
39
16
39
16
39
47
8
% L
% Met:
0
0
0
0
0
0
0
24
0
0
8
39
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
39
0
0
0
8
0
8
8
0
8
0
0
0
% P
% Gln:
0
0
0
8
0
8
0
0
0
0
0
0
0
16
8
% Q
% Arg:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
24
8
31
8
0
8
8
0
8
8
8
0
8
24
% S
% Thr:
8
8
0
0
0
0
0
24
0
0
0
8
0
0
8
% T
% Val:
8
0
0
0
0
0
0
8
0
8
8
0
16
0
0
% V
% Trp:
0
0
0
8
8
0
16
0
0
0
24
0
39
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _