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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFAS
All Species:
20
Human Site:
Y8
Identified Species:
36.67
UniProt:
O15067
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15067
NP_036525
1338
144724
Y8
M
S
P
V
L
H
F
Y
V
R
P
S
G
H
E
Chimpanzee
Pan troglodytes
XP_511854
1397
150781
Y67
M
S
P
V
L
H
F
Y
V
R
P
S
G
H
E
Rhesus Macaque
Macaca mulatta
XP_001112405
1335
144369
Y8
M
S
P
V
F
H
F
Y
V
R
P
S
G
H
E
Dog
Lupus familis
XP_850167
1368
147436
Y8
M
T
S
V
L
H
F
Y
V
H
P
S
G
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUR0
1337
144611
Y8
M
A
P
V
L
H
F
Y
V
R
P
S
G
H
E
Rat
Rattus norvegicus
NP_001099261
1271
136879
S10
L
L
G
S
P
G
W
S
L
A
P
M
I
C
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038667
1314
142462
R8
M
P
V
V
R
F
Y
R
T
E
E
T
G
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35421
1354
148067
D8
M
V
I
L
R
Y
Y
D
V
Q
A
H
S
A
A
Honey Bee
Apis mellifera
XP_625036
1243
138433
I9
D
I
I
R
F
Y
K
I
P
G
L
K
S
G
Q
Nematode Worm
Caenorhab. elegans
Q19311
1343
148611
L8
M
T
K
F
H
V
K
L
Y
A
K
A
V
E
S
Sea Urchin
Strong. purpuratus
XP_781955
1205
129101
T8
M
V
I
I
H
Y
F
T
V
P
A
L
S
D
G
Poplar Tree
Populus trichocarpa
XP_002315209
1377
150616
F59
P
V
Q
E
L
I
H
F
Y
R
I
P
L
I
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8D3
1387
151761
F70
P
A
A
E
V
I
H
F
Y
R
V
P
L
I
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
97.1
87.5
N.A.
88.5
84
N.A.
N.A.
N.A.
N.A.
63.2
N.A.
50.5
50.1
47.5
52.4
Protein Similarity:
100
95.2
98
91.6
N.A.
92.8
88.6
N.A.
N.A.
N.A.
N.A.
75.1
N.A.
66
66.2
64.1
65.4
P-Site Identity:
100
100
93.3
80
N.A.
93.3
6.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
13.3
0
6.6
20
P-Site Similarity:
100
100
93.3
86.6
N.A.
100
26.6
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
40
13.3
20
33.3
Percent
Protein Identity:
50.3
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
65.2
N.A.
N.A.
65.3
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
0
0
0
0
0
16
16
8
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
8
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
16
0
0
0
0
0
8
8
0
0
16
39
% E
% Phe:
0
0
0
8
16
8
47
16
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
0
0
0
8
0
0
47
8
8
% G
% His:
0
0
0
0
16
39
16
0
0
8
0
8
0
39
0
% H
% Ile:
0
8
24
8
0
16
0
8
0
0
8
0
8
16
0
% I
% Lys:
0
0
8
0
0
0
16
0
0
0
8
8
0
0
0
% K
% Leu:
8
8
0
8
39
0
0
8
8
0
8
8
16
0
0
% L
% Met:
70
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
16
8
31
0
8
0
0
0
8
8
47
16
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
24
% Q
% Arg:
0
0
0
8
16
0
0
8
0
47
0
0
0
0
0
% R
% Ser:
0
24
8
8
0
0
0
8
0
0
0
39
24
0
8
% S
% Thr:
0
16
0
0
0
0
0
8
8
0
0
8
0
0
0
% T
% Val:
0
24
8
47
8
8
0
0
54
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
24
16
39
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _