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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCF2L All Species: 19.39
Human Site: S1003 Identified Species: 47.41
UniProt: O15068 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15068 NP_001106203.1 1137 128109 S1003 S L E G Y V S S A P L T K P P
Chimpanzee Pan troglodytes XP_509745 1123 126012 S971 S L E G Y V S S A P L T K P P
Rhesus Macaque Macaca mulatta XP_001103476 1325 144488 S1173 S L E G Y V S S A P L P K P P
Dog Lupus familis XP_542673 1152 129437 P944 S L E G Y M S P S S L P K P P
Cat Felis silvestris
Mouse Mus musculus Q64096 1149 129131 S1004 S L E G Y V S S S L P K P P E
Rat Rattus norvegicus Q63406 1149 129391 S1004 C L E G C V S S S L P K P P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515228 1441 162747 S1072 S L E G C I G S G T A P K F P
Chicken Gallus gallus XP_416947 1249 142097 T1047 S L E G Y V T T V A P K Y P E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922183 1311 148260 A1087 T T T D P S S A A L F K N N D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392741 1340 152741 G1215 E A Q S S I S G S L R T L S V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.8 69.5 81.9 N.A. 85.9 85.5 N.A. 60.5 68.4 N.A. 51.4 N.A. N.A. 28 N.A. N.A.
Protein Similarity: 100 95.5 74.9 87.3 N.A. 91.4 91.3 N.A. 69.5 79.1 N.A. 64.9 N.A. N.A. 44.4 N.A. N.A.
P-Site Identity: 100 100 93.3 66.6 N.A. 60 46.6 N.A. 46.6 46.6 N.A. 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 100 93.3 80 N.A. 66.6 53.3 N.A. 53.3 60 N.A. 26.6 N.A. N.A. 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 10 40 10 10 0 0 0 0 % A
% Cys: 10 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 10 0 80 0 0 0 0 0 0 0 0 0 0 0 30 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % F
% Gly: 0 0 0 80 0 0 10 10 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 40 50 0 0 % K
% Leu: 0 80 0 0 0 0 0 0 0 40 40 0 10 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % N
% Pro: 0 0 0 0 10 0 0 10 0 30 30 30 20 70 50 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 70 0 0 10 10 10 80 60 40 10 0 0 0 10 0 % S
% Thr: 10 10 10 0 0 0 10 10 0 10 0 30 0 0 0 % T
% Val: 0 0 0 0 0 60 0 0 10 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 60 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _