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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NACAD All Species: 5.15
Human Site: S1267 Identified Species: 22.67
UniProt: O15069 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15069 NP_001139806.1 1562 161101 S1267 E D E E P P G S L G L P P P Q
Chimpanzee Pan troglodytes XP_519080 1226 128677 V966 K N A A L P T V P E P A A L D
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q5SWP3 1504 156745 S1183 E E E K P P A S R G P M P R A
Rat Rattus norvegicus XP_001069804 1576 164995 S1286 E E E K P S A S H G L R S R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418516 1396 146149 A1063 P K A V A P V A I P L P A P C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690863 2317 256346 A2030 N H E S E R T A M T A I P C R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.1 N.A. N.A. N.A. 49.7 58.2 N.A. N.A. 25.9 N.A. 22.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 45.5 N.A. N.A. N.A. 60.1 68.6 N.A. N.A. 39.8 N.A. 35.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 N.A. N.A. N.A. 46.6 40 N.A. N.A. 26.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 N.A. N.A. N.A. 60 53.3 N.A. N.A. 40 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 34 17 17 0 34 34 0 0 17 17 34 0 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 17 % C
% Asp: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 17 % D
% Glu: 50 34 67 17 17 0 0 0 0 17 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 17 0 0 50 0 0 0 0 0 % G
% His: 0 17 0 0 0 0 0 0 17 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 17 0 0 17 0 0 0 % I
% Lys: 17 17 0 34 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 17 0 0 0 17 0 50 0 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 17 0 0 17 0 0 0 % M
% Asn: 17 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 17 0 0 0 50 67 0 0 17 17 34 34 50 34 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % Q
% Arg: 0 0 0 0 0 17 0 0 17 0 0 17 0 34 17 % R
% Ser: 0 0 0 17 0 17 0 50 0 0 0 0 17 0 0 % S
% Thr: 0 0 0 0 0 0 34 0 0 17 0 0 0 0 0 % T
% Val: 0 0 0 17 0 0 17 17 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _