KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMAD7
All Species:
36.36
Human Site:
Y338
Identified Species:
61.54
UniProt:
O15105
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15105
NP_005895.1
426
46426
Y338
W
V
Y
N
R
S
S
Y
P
I
F
I
K
S
A
Chimpanzee
Pan troglodytes
XP_512124
426
46437
Y338
W
V
Y
N
R
S
S
Y
P
I
F
I
K
S
A
Rhesus Macaque
Macaca mulatta
XP_001087560
426
46226
Y338
W
V
Y
N
R
S
S
Y
P
I
F
I
K
S
A
Dog
Lupus familis
XP_850493
430
46498
Y342
W
V
Y
N
R
S
S
Y
P
I
F
I
K
S
A
Cat
Felis silvestris
Mouse
Mus musculus
O35253
426
46423
Y338
W
V
Y
N
R
S
S
Y
P
I
F
I
K
S
A
Rat
Rattus norvegicus
O88406
426
46439
Y338
W
V
Y
N
R
S
S
Y
P
I
F
I
K
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509923
178
20616
P91
V
Y
N
R
S
S
Y
P
I
F
I
K
S
A
T
Chicken
Gallus gallus
Q9W734
431
47806
H342
W
A
Y
N
R
S
E
H
P
I
F
V
N
S
P
Frog
Xenopus laevis
NP_001081017
382
42694
Y294
W
V
Y
N
R
S
S
Y
P
I
F
I
K
S
A
Zebra Danio
Brachydanio rerio
Q9I9P9
468
52435
S354
F
A
E
C
L
S
D
S
A
I
F
V
Q
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42003
455
50486
S341
Y
A
E
C
L
S
D
S
A
I
F
V
Q
S
R
Honey Bee
Apis mellifera
XP_396816
251
28007
L164
I
F
V
N
S
P
T
L
D
D
P
E
S
R
T
Nematode Worm
Caenorhab. elegans
P45897
570
63351
T465
T
P
N
E
S
S
F
T
V
F
D
I
R
W
A
Sea Urchin
Strong. purpuratus
XP_798238
371
42051
Y283
W
I
Y
N
R
S
N
Y
A
L
F
V
N
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.8
95.8
N.A.
98.1
97.8
N.A.
40.8
51.5
77.2
22.6
N.A.
20.2
30.7
20.5
43.4
Protein Similarity:
100
99.7
96.7
96.7
N.A.
98.5
98.5
N.A.
41.3
64.5
81.9
37.3
N.A.
36
39.6
35
57.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
60
100
26.6
N.A.
26.6
6.6
20
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
73.3
100
46.6
N.A.
46.6
13.3
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
0
0
0
0
0
22
0
0
0
0
8
58
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
15
0
8
8
8
0
0
0
0
% D
% Glu:
0
0
15
8
0
0
8
0
0
0
0
8
0
0
0
% E
% Phe:
8
8
0
0
0
0
8
0
0
15
79
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
8
72
8
58
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
50
0
0
% K
% Leu:
0
0
0
0
15
0
0
8
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
72
0
0
8
0
0
0
0
0
15
0
0
% N
% Pro:
0
8
0
0
0
8
0
8
58
0
8
0
0
0
22
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% Q
% Arg:
0
0
0
8
65
0
0
0
0
0
0
0
8
8
8
% R
% Ser:
0
0
0
0
22
93
50
15
0
0
0
0
15
79
0
% S
% Thr:
8
0
0
0
0
0
8
8
0
0
0
0
0
0
15
% T
% Val:
8
50
8
0
0
0
0
0
8
0
0
29
0
0
0
% V
% Trp:
65
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
8
8
65
0
0
0
8
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _