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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHUK
All Species:
13.64
Human Site:
S576
Identified Species:
30
UniProt:
O15111
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15111
NP_001269.3
745
84654
S576
K
Q
L
K
H
R
P
S
D
H
S
Y
S
D
S
Chimpanzee
Pan troglodytes
XP_001167720
745
84642
S576
K
Q
L
K
H
R
P
S
D
H
S
Y
S
D
S
Rhesus Macaque
Macaca mulatta
XP_001107171
745
84635
S576
K
Q
L
K
H
R
P
S
D
H
S
Y
S
D
S
Dog
Lupus familis
XP_534990
745
84877
S576
K
Q
L
K
H
R
P
S
D
H
S
Y
S
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60680
745
84710
P576
K
Q
L
K
H
R
P
P
D
H
L
Y
S
D
S
Rat
Rattus norvegicus
Q9QY78
757
86848
R579
R
R
L
R
E
K
P
R
D
Q
R
T
E
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513035
723
82400
P554
K
Q
L
K
H
R
S
P
D
H
S
Y
S
D
S
Chicken
Gallus gallus
Q5ZJB4
759
86125
P590
K
Q
L
K
T
R
P
P
D
H
A
Y
S
D
S
Frog
Xenopus laevis
Q6GM53
743
85134
P574
K
Q
L
K
P
R
S
P
D
K
A
Y
S
D
S
Zebra Danio
Brachydanio rerio
Q4G3H4
758
87129
K577
K
Q
L
K
A
K
C
K
M
P
D
P
Q
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEZ5
751
86354
N595
K
D
M
V
K
T
T
N
Q
L
R
K
E
V
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
97.7
N.A.
95.5
49.1
N.A.
80.1
80.1
72.6
62.9
N.A.
24.3
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.8
98.7
N.A.
97.4
66.7
N.A.
86.9
88.9
85.6
77.8
N.A.
45
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
20
N.A.
86.6
80
66.6
26.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
46.6
N.A.
86.6
86.6
73.3
33.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
0
0
0
0
82
0
10
0
0
73
10
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
19
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% G
% His:
0
0
0
0
55
0
0
0
0
64
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
91
0
0
82
10
19
0
10
0
10
0
10
0
0
0
% K
% Leu:
0
0
91
0
0
0
0
0
0
10
10
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
64
37
0
10
0
10
0
0
0
% P
% Gln:
0
82
0
0
0
0
0
0
10
10
0
0
10
0
0
% Q
% Arg:
10
10
0
10
0
73
0
10
0
0
19
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
19
37
0
0
46
0
73
0
73
% S
% Thr:
0
0
0
0
10
10
10
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _