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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBX3 All Species: 21.21
Human Site: S358 Identified Species: 38.89
UniProt: O15119 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15119 NP_005987.3 743 79389 S358 Q A S S P A A S T V G T S N L
Chimpanzee Pan troglodytes XP_001154426 743 79366 S358 Q A S S P A V S T V G T S N L
Rhesus Macaque Macaca mulatta XP_001111920 743 79280 S358 Q A S S P A V S T V G T S N L
Dog Lupus familis XP_534692 710 75612 S338 Q S S S P A V S T V G T S N L
Cat Felis silvestris
Mouse Mus musculus P70324 741 79244 V358 S S P A V S I V G T S N L K D
Rat Rattus norvegicus Q7TST9 743 79316 S358 Q A S S P A V S T V G T S N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510506 774 81648 S365 Q S S S P A V S T V G T S N L
Chicken Gallus gallus O73718 414 46293 K62 S L P G A L A K P I M D Q L V
Frog Xenopus laevis Q6PCL0 691 75547 L337 A A P S P L R L H R T N R E E
Zebra Danio Brachydanio rerio Q7ZTU9 687 75316 F335 P V S S P L R F N R G S R D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24432 972 102538 L587 V G P P Q S P L L P L S H S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19691 423 46979 W71 E L D E R E L W Q Q F S Q C G
Sea Urchin Strong. purpuratus NP_001123280 649 70697 P297 I D H G D D I P S D Q E A E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.3 88.2 N.A. 93.6 94.3 N.A. 78.5 48.5 54.5 55.1 N.A. 29.8 N.A. 32.4 39.1
Protein Similarity: 100 99.8 99.5 90 N.A. 95.9 95.9 N.A. 83.3 51.1 66.3 67.2 N.A. 39.2 N.A. 41.8 51.4
P-Site Identity: 100 93.3 93.3 86.6 N.A. 0 93.3 N.A. 86.6 6.6 20 26.6 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 20 93.3 N.A. 93.3 20 20 40 N.A. 26.6 N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 39 0 8 8 47 16 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 8 8 0 8 8 0 0 0 8 0 8 0 8 16 % D
% Glu: 8 0 0 8 0 8 0 0 0 0 0 8 0 16 8 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % F
% Gly: 0 8 0 16 0 0 0 0 8 0 54 0 0 0 8 % G
% His: 0 0 8 0 0 0 0 0 8 0 0 0 8 0 0 % H
% Ile: 8 0 0 0 0 0 16 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % K
% Leu: 0 16 0 0 0 24 8 16 8 0 8 0 8 8 54 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 16 0 47 0 % N
% Pro: 8 0 31 8 62 0 8 8 8 8 0 0 0 0 0 % P
% Gln: 47 0 0 0 8 0 0 0 8 8 8 0 16 0 0 % Q
% Arg: 0 0 0 0 8 0 16 0 0 16 0 0 16 0 0 % R
% Ser: 16 24 54 62 0 16 0 47 8 0 8 24 47 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 47 8 8 47 0 0 8 % T
% Val: 8 8 0 0 8 0 39 8 0 47 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _