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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX3
All Species:
18.79
Human Site:
S381
Identified Species:
34.44
UniProt:
O15119
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15119
NP_005987.3
743
79389
S381
E
S
D
A
E
A
E
S
K
E
E
H
G
P
E
Chimpanzee
Pan troglodytes
XP_001154426
743
79366
S381
E
S
D
A
E
A
E
S
K
E
E
H
G
P
E
Rhesus Macaque
Macaca mulatta
XP_001111920
743
79280
S381
E
S
D
A
E
A
E
S
K
E
E
H
G
P
E
Dog
Lupus familis
XP_534692
710
75612
S361
E
S
D
A
E
A
D
S
K
E
E
H
G
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P70324
741
79244
E381
D
A
E
A
E
S
K
E
E
H
G
P
E
A
C
Rat
Rattus norvegicus
Q7TST9
743
79316
S381
E
S
D
A
E
A
E
S
K
E
E
H
G
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510506
774
81648
K388
G
D
S
D
A
E
V
K
D
E
P
G
H
E
V
Chicken
Gallus gallus
O73718
414
46293
A85
F
S
S
L
G
Q
Q
A
A
A
H
L
R
P
L
Frog
Xenopus laevis
Q6PCL0
691
75547
R360
E
L
D
R
R
E
V
R
S
A
R
G
H
S
P
Zebra Danio
Brachydanio rerio
Q7ZTU9
687
75316
R358
E
M
D
H
Q
N
D
R
C
G
G
S
S
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
F610
S
A
A
L
A
A
W
F
N
H
L
A
G
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
Y94
G
R
R
I
F
P
A
Y
R
V
K
I
S
G
L
Sea Urchin
Strong. purpuratus
NP_001123280
649
70697
R320
D
R
H
E
E
R
E
R
G
H
S
S
H
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
88.2
N.A.
93.6
94.3
N.A.
78.5
48.5
54.5
55.1
N.A.
29.8
N.A.
32.4
39.1
Protein Similarity:
100
99.8
99.5
90
N.A.
95.9
95.9
N.A.
83.3
51.1
66.3
67.2
N.A.
39.2
N.A.
41.8
51.4
P-Site Identity:
100
100
100
93.3
N.A.
13.3
100
N.A.
6.6
13.3
13.3
13.3
N.A.
13.3
N.A.
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
53.3
100
N.A.
6.6
26.6
13.3
26.6
N.A.
20
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
47
16
47
8
8
8
16
0
8
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
16
8
54
8
0
0
16
0
8
0
0
0
0
0
0
% D
% Glu:
54
0
8
8
54
16
39
8
8
47
39
0
8
16
39
% E
% Phe:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
16
0
0
0
8
0
0
0
8
8
16
16
47
8
8
% G
% His:
0
0
8
8
0
0
0
0
0
24
8
39
24
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
8
39
0
8
0
0
0
0
% K
% Leu:
0
8
0
16
0
0
0
0
0
0
8
8
0
0
24
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
8
8
0
47
16
% P
% Gln:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
16
8
8
8
8
0
24
8
0
8
0
8
0
0
% R
% Ser:
8
47
16
0
0
8
0
39
8
0
8
16
16
16
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
16
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _