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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX3
All Species:
15.76
Human Site:
S400
Identified Species:
28.89
UniProt:
O15119
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15119
NP_005987.3
743
79389
S400
A
K
I
S
T
T
T
S
E
E
P
C
R
D
K
Chimpanzee
Pan troglodytes
XP_001154426
743
79366
S400
A
K
I
S
T
T
T
S
E
E
P
C
R
D
K
Rhesus Macaque
Macaca mulatta
XP_001111920
743
79280
S400
A
K
I
S
T
T
T
S
E
E
P
C
R
D
K
Dog
Lupus familis
XP_534692
710
75612
S380
A
K
I
S
T
T
T
S
E
E
P
S
R
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P70324
741
79244
E400
I
S
T
T
T
A
E
E
P
G
R
D
K
G
S
Rat
Rattus norvegicus
Q7TST9
743
79316
A400
A
K
I
S
T
T
T
A
E
E
P
G
R
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510506
774
81648
E407
K
I
S
T
T
T
S
E
D
P
P
R
E
K
G
Chicken
Gallus gallus
O73718
414
46293
D104
P
E
E
E
V
E
D
D
P
K
V
H
L
E
A
Frog
Xenopus laevis
Q6PCL0
691
75547
L379
S
P
P
S
S
P
R
L
E
D
R
G
K
D
K
Zebra Danio
Brachydanio rerio
Q7ZTU9
687
75316
S377
S
S
P
F
R
S
R
S
E
D
W
G
R
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
A629
E
H
A
A
A
A
A
A
N
A
S
A
E
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
L113
Q
Y
F
V
M
M
D
L
V
P
A
D
E
H
R
Sea Urchin
Strong. purpuratus
NP_001123280
649
70697
P339
S
E
G
R
L
N
G
P
G
L
N
K
C
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
88.2
N.A.
93.6
94.3
N.A.
78.5
48.5
54.5
55.1
N.A.
29.8
N.A.
32.4
39.1
Protein Similarity:
100
99.8
99.5
90
N.A.
95.9
95.9
N.A.
83.3
51.1
66.3
67.2
N.A.
39.2
N.A.
41.8
51.4
P-Site Identity:
100
100
100
93.3
N.A.
6.6
86.6
N.A.
20
0
26.6
26.6
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
20
93.3
N.A.
40
20
53.3
53.3
N.A.
20
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
8
8
8
16
8
16
0
8
8
8
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
24
8
0
0
% C
% Asp:
0
0
0
0
0
0
16
8
8
16
0
16
0
54
0
% D
% Glu:
8
16
8
8
0
8
8
16
54
39
0
0
24
16
0
% E
% Phe:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
8
0
8
8
0
24
0
8
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
8
8
39
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
39
0
0
0
0
0
0
0
8
0
8
16
16
54
% K
% Leu:
0
0
0
0
8
0
0
16
0
8
0
0
8
0
0
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
8
0
0
0
0
% N
% Pro:
8
8
16
0
0
8
0
8
16
16
47
0
0
0
8
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
0
16
0
0
0
16
8
47
0
8
% R
% Ser:
24
16
8
47
8
8
8
39
0
0
8
8
0
0
8
% S
% Thr:
0
0
8
16
54
47
39
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _