KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX3
All Species:
26.97
Human Site:
S443
Identified Species:
49.44
UniProt:
O15119
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15119
NP_005987.3
743
79389
S443
R
H
S
P
A
T
I
S
S
S
T
R
G
L
G
Chimpanzee
Pan troglodytes
XP_001154426
743
79366
S443
R
H
S
P
A
T
I
S
S
S
T
R
G
L
G
Rhesus Macaque
Macaca mulatta
XP_001111920
743
79280
S443
R
H
S
P
A
T
I
S
S
S
T
R
G
L
G
Dog
Lupus familis
XP_534692
710
75612
S426
R
H
S
P
A
T
I
S
S
S
T
R
G
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P70324
741
79244
S443
R
H
S
P
A
T
I
S
S
S
T
R
V
P
G
Rat
Rattus norvegicus
Q7TST9
743
79316
S445
R
H
S
P
A
T
I
S
S
S
T
R
V
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510506
774
81648
S458
R
H
S
P
A
T
I
S
S
S
T
R
G
P
G
Chicken
Gallus gallus
O73718
414
46293
D146
K
V
R
C
T
G
L
D
K
K
A
K
Y
I
L
Frog
Xenopus laevis
Q6PCL0
691
75547
V421
R
S
L
E
K
D
K
V
E
S
R
R
K
E
D
Zebra Danio
Brachydanio rerio
Q7ZTU9
687
75316
R419
D
K
L
E
S
R
S
R
K
D
T
D
S
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
S672
G
G
A
F
R
P
T
S
T
G
S
P
K
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
W155
S
P
S
T
G
E
H
W
M
S
K
G
A
N
F
Sea Urchin
Strong. purpuratus
NP_001123280
649
70697
H381
E
R
R
M
D
G
K
H
R
L
S
Q
D
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
88.2
N.A.
93.6
94.3
N.A.
78.5
48.5
54.5
55.1
N.A.
29.8
N.A.
32.4
39.1
Protein Similarity:
100
99.8
99.5
90
N.A.
95.9
95.9
N.A.
83.3
51.1
66.3
67.2
N.A.
39.2
N.A.
41.8
51.4
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
93.3
0
20
6.6
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
93.3
26.6
20
13.3
N.A.
26.6
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
54
0
0
0
0
0
8
0
8
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
8
0
8
0
8
0
8
8
8
8
% D
% Glu:
8
0
0
16
0
8
0
0
8
0
0
0
0
16
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
8
0
0
8
16
0
0
0
8
0
8
39
0
54
% G
% His:
0
54
0
0
0
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
54
0
0
0
0
0
0
8
0
% I
% Lys:
8
8
0
0
8
0
16
0
16
8
8
8
16
0
8
% K
% Leu:
0
0
16
0
0
0
8
0
0
8
0
0
0
31
8
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
54
0
8
0
0
0
0
0
8
0
24
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
62
8
16
0
8
8
0
8
8
0
8
62
0
0
0
% R
% Ser:
8
8
62
0
8
0
8
62
54
70
16
0
8
8
8
% S
% Thr:
0
0
0
8
8
54
8
0
8
0
62
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
8
0
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _