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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX3
All Species:
24.55
Human Site:
S622
Identified Species:
45
UniProt:
O15119
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15119
NP_005987.3
743
79389
S622
S
S
A
A
A
S
S
S
V
H
R
H
P
F
L
Chimpanzee
Pan troglodytes
XP_001154426
743
79366
S622
S
S
A
A
A
S
S
S
V
H
R
H
P
F
L
Rhesus Macaque
Macaca mulatta
XP_001111920
743
79280
S622
S
S
A
A
A
S
S
S
V
H
R
H
P
F
L
Dog
Lupus familis
XP_534692
710
75612
A589
R
H
L
A
F
P
N
A
L
L
S
V
R
E
P
Cat
Felis silvestris
Mouse
Mus musculus
P70324
741
79244
S620
S
T
A
A
A
S
S
S
V
H
R
H
P
F
L
Rat
Rattus norvegicus
Q7TST9
743
79316
S622
S
S
A
A
A
S
S
S
V
H
R
H
P
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510506
774
81648
S650
S
T
A
A
A
A
A
S
S
S
A
H
R
H
S
Chicken
Gallus gallus
O73718
414
46293
K297
N
G
R
R
E
K
R
K
Q
L
T
L
Q
S
M
Frog
Xenopus laevis
Q6PCL0
691
75547
S572
A
A
A
A
A
A
A
S
A
M
P
A
T
S
A
Zebra Danio
Brachydanio rerio
Q7ZTU9
687
75316
A570
A
A
A
A
A
A
S
A
L
P
A
S
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
G828
G
G
G
G
G
L
G
G
G
V
V
E
N
G
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
S306
P
S
Q
T
P
T
T
S
S
L
S
T
S
T
T
Sea Urchin
Strong. purpuratus
NP_001123280
649
70697
A532
S
L
Y
S
E
A
A
A
L
S
S
M
Y
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
88.2
N.A.
93.6
94.3
N.A.
78.5
48.5
54.5
55.1
N.A.
29.8
N.A.
32.4
39.1
Protein Similarity:
100
99.8
99.5
90
N.A.
95.9
95.9
N.A.
83.3
51.1
66.3
67.2
N.A.
39.2
N.A.
41.8
51.4
P-Site Identity:
100
100
100
6.6
N.A.
93.3
100
N.A.
40
0
26.6
26.6
N.A.
0
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
60
13.3
53.3
60
N.A.
0
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
62
70
62
31
24
24
8
0
16
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
16
0
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
39
0
% F
% Gly:
8
16
8
8
8
0
8
8
8
0
0
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
39
0
47
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
8
0
0
8
0
0
24
24
0
8
0
0
39
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
8
0
0
0
8
8
0
0
0
8
8
0
39
0
16
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
8
0
8
8
0
0
8
0
0
0
39
0
16
0
0
% R
% Ser:
54
39
0
8
0
39
47
62
16
16
24
8
16
24
16
% S
% Thr:
0
16
0
8
0
8
8
0
0
0
8
8
8
8
16
% T
% Val:
0
0
0
0
0
0
0
0
39
8
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _