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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX3
All Species:
25.76
Human Site:
Y643
Identified Species:
47.22
UniProt:
O15119
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15119
NP_005987.3
743
79389
Y643
P
R
L
R
Y
S
P
Y
S
I
P
V
P
V
P
Chimpanzee
Pan troglodytes
XP_001154426
743
79366
Y643
P
R
L
R
Y
S
P
Y
S
I
P
V
P
V
P
Rhesus Macaque
Macaca mulatta
XP_001111920
743
79280
Y643
P
R
L
R
Y
S
P
Y
S
I
P
V
P
V
P
Dog
Lupus familis
XP_534692
710
75612
Y610
S
V
G
S
R
G
P
Y
S
I
F
M
P
V
P
Cat
Felis silvestris
Mouse
Mus musculus
P70324
741
79244
Y641
P
R
L
R
Y
S
P
Y
S
I
P
V
P
V
P
Rat
Rattus norvegicus
Q7TST9
743
79316
Y643
P
R
L
R
Y
S
P
Y
S
I
P
V
P
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510506
774
81648
Y671
P
R
L
R
Y
N
P
Y
P
I
P
V
P
L
P
Chicken
Gallus gallus
O73718
414
46293
S318
Q
K
K
E
N
P
T
S
D
E
S
S
N
E
Q
Frog
Xenopus laevis
Q6PCL0
691
75547
R593
N
P
F
L
S
S
T
R
P
R
L
R
F
N
P
Zebra Danio
Brachydanio rerio
Q7ZTU9
687
75316
T591
N
P
F
L
S
S
S
T
R
P
R
L
R
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
H849
P
R
P
R
P
A
S
H
S
P
P
T
R
P
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
F327
H
P
L
R
S
P
Q
F
C
I
P
P
P
I
D
Sea Urchin
Strong. purpuratus
NP_001123280
649
70697
L553
I
L
N
G
H
P
R
L
R
F
S
P
Y
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
88.2
N.A.
93.6
94.3
N.A.
78.5
48.5
54.5
55.1
N.A.
29.8
N.A.
32.4
39.1
Protein Similarity:
100
99.8
99.5
90
N.A.
95.9
95.9
N.A.
83.3
51.1
66.3
67.2
N.A.
39.2
N.A.
41.8
51.4
P-Site Identity:
100
100
100
46.6
N.A.
100
100
N.A.
80
0
13.3
6.6
N.A.
33.3
N.A.
33.3
0
P-Site Similarity:
100
100
100
53.3
N.A.
100
100
N.A.
93.3
6.6
13.3
13.3
N.A.
46.6
N.A.
46.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
16
0
0
0
0
8
0
8
8
0
8
8
0
% F
% Gly:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
62
0
0
0
8
8
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
54
16
0
0
0
8
0
0
8
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
16
0
8
0
8
8
0
0
0
0
0
0
8
8
8
% N
% Pro:
54
24
8
0
8
24
54
0
16
16
62
16
62
8
62
% P
% Gln:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Q
% Arg:
0
54
0
62
8
0
8
8
16
8
8
8
16
0
0
% R
% Ser:
8
0
0
8
24
54
16
8
54
0
16
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
16
8
0
0
0
8
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
47
0
47
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
47
0
0
54
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _