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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEGS1 All Species: 29.7
Human Site: Y14 Identified Species: 65.33
UniProt: O15121 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15121 NP_003667.1 323 37866 Y14 R E D F E W V Y T D Q P H A D
Chimpanzee Pan troglodytes XP_514228 436 48061 A127 F L C P Q V G A L S S P H S L
Rhesus Macaque Macaca mulatta XP_001096845 323 38016 Y14 R E D F E W V Y T D Q P H A D
Dog Lupus familis XP_547516 434 48604 A125 A S S G W A A A A R S V T R L
Cat Felis silvestris
Mouse Mus musculus O09005 323 38223 Y14 R E E F E W V Y T D Q P H A A
Rat Rattus norvegicus Q5XIF5 323 38037 Y14 R E E F E W V Y T D Q P H A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512442 355 41134 N46 P R A S G L L N P F L N F S H
Chicken Gallus gallus Q5F3C1 323 37957 Y14 R E D F E W V Y T D Q P H A D
Frog Xenopus laevis NP_001087100 322 37718 Y14 R G D F E W V Y S D Q P H T Q
Zebra Danio Brachydanio rerio NP_997865 323 38133 Y14 R E D F E W V Y T D Q P H A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_476594 321 37195 Y14 R T D F E W V Y T E E P H A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71 97.5 64.9 N.A. 85.4 85.4 N.A. 72.9 82 65.3 73.9 N.A. 60.9 N.A. N.A. N.A.
Protein Similarity: 100 71.5 98.1 70 N.A. 93.5 93.5 N.A. 81.9 91.9 80.5 86 N.A. 74.9 N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 0 N.A. 86.6 86.6 N.A. 0 100 73.3 100 N.A. 73.3 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 0 N.A. 93.3 93.3 N.A. 13.3 100 80 100 N.A. 86.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 10 10 19 10 0 0 0 0 64 19 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 55 0 0 0 0 0 0 64 0 0 0 0 37 % D
% Glu: 0 55 19 0 73 0 0 0 0 10 10 0 0 0 0 % E
% Phe: 10 0 0 73 0 0 0 0 0 10 0 0 10 0 0 % F
% Gly: 0 10 0 10 10 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 82 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 10 10 0 10 0 10 0 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % N
% Pro: 10 0 0 10 0 0 0 0 10 0 0 82 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 64 0 0 0 10 % Q
% Arg: 73 10 0 0 0 0 0 0 0 10 0 0 0 10 0 % R
% Ser: 0 10 10 10 0 0 0 0 10 10 19 0 0 19 10 % S
% Thr: 0 10 0 0 0 0 0 0 64 0 0 0 10 10 0 % T
% Val: 0 0 0 0 0 10 73 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 10 73 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 73 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _