KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEGS1
All Species:
38.79
Human Site:
Y309
Identified Species:
85.33
UniProt:
O15121
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15121
NP_003667.1
323
37866
Y309
M
D
D
T
I
S
P
Y
S
R
M
K
R
H
Q
Chimpanzee
Pan troglodytes
XP_514228
436
48061
Y422
M
D
D
T
I
S
P
Y
S
R
M
K
R
H
Q
Rhesus Macaque
Macaca mulatta
XP_001096845
323
38016
Y309
M
D
D
T
I
S
P
Y
S
R
M
K
R
H
Q
Dog
Lupus familis
XP_547516
434
48604
Y420
T
D
D
T
I
S
P
Y
S
R
M
K
R
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
O09005
323
38223
Y309
T
D
D
T
I
S
P
Y
S
R
M
K
R
P
P
Rat
Rattus norvegicus
Q5XIF5
323
38037
Y309
M
D
D
T
I
S
P
Y
S
R
M
K
R
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512442
355
41134
Y341
M
D
D
S
I
S
P
Y
S
R
M
K
R
H
L
Chicken
Gallus gallus
Q5F3C1
323
37957
Y309
M
D
D
T
I
S
P
Y
S
R
M
K
R
Q
L
Frog
Xenopus laevis
NP_001087100
322
37718
Y309
F
E
K
E
L
G
P
Y
S
R
I
K
R
K
C
Zebra Danio
Brachydanio rerio
NP_997865
323
38133
Y309
M
D
D
Q
L
S
P
Y
S
R
V
K
R
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476594
321
37195
Y309
M
D
P
A
V
G
P
Y
A
R
V
K
R
R
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71
97.5
64.9
N.A.
85.4
85.4
N.A.
72.9
82
65.3
73.9
N.A.
60.9
N.A.
N.A.
N.A.
Protein Similarity:
100
71.5
98.1
70
N.A.
93.5
93.5
N.A.
81.9
91.9
80.5
86
N.A.
74.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
86.6
86.6
40
66.6
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
93.3
86.6
60
80
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
91
82
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
0
% H
% Ile:
0
0
0
0
73
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
100
0
19
0
% K
% Leu:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
28
% L
% Met:
73
0
0
0
0
0
0
0
0
0
73
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
100
0
0
0
0
0
0
19
19
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
46
% Q
% Arg:
0
0
0
0
0
0
0
0
0
100
0
0
100
10
0
% R
% Ser:
0
0
0
10
0
82
0
0
91
0
0
0
0
0
0
% S
% Thr:
19
0
0
64
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _