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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPFF
All Species:
8.18
Human Site:
S90
Identified Species:
36
UniProt:
O15130
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15130
NP_003708.1
113
12440
S90
S
W
R
N
E
W
L
S
P
R
A
G
E
G
L
Chimpanzee
Pan troglodytes
XP_001138078
113
12377
S90
S
W
R
N
E
R
L
S
P
R
A
G
E
G
L
Rhesus Macaque
Macaca mulatta
XP_001106733
113
12506
S90
S
W
S
N
E
R
L
S
P
R
A
G
E
G
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVA8
114
12993
F82
F
L
F
Q
P
Q
R
F
G
R
S
A
W
G
S
Rat
Rattus norvegicus
Q9WVA9
114
13133
W90
G
R
N
A
W
G
P
W
S
K
E
Q
L
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001092116
126
14024
H103
V
M
L
E
N
E
I
H
P
R
D
W
E
G
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
90.2
N.A.
N.A.
60.5
62.2
N.A.
N.A.
N.A.
N.A.
N.A.
32.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
92.9
N.A.
N.A.
68.4
69.3
N.A.
N.A.
N.A.
N.A.
N.A.
49.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
N.A.
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
86.6
N.A.
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
0
0
0
0
50
17
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% D
% Glu:
0
0
0
17
50
17
0
0
0
0
17
0
67
0
0
% E
% Phe:
17
0
17
0
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
17
0
0
17
0
0
50
0
84
0
% G
% His:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% K
% Leu:
0
17
17
0
0
0
50
0
0
0
0
0
17
0
50
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
50
17
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
17
0
17
0
67
0
0
0
0
0
17
% P
% Gln:
0
0
0
17
0
17
0
0
0
0
0
17
0
0
0
% Q
% Arg:
0
17
34
0
0
34
17
0
0
84
0
0
0
0
0
% R
% Ser:
50
0
17
0
0
0
0
50
17
0
17
0
0
17
17
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
50
0
0
17
17
0
17
0
0
0
17
17
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _