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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNA5
All Species:
30.91
Human Site:
S221
Identified Species:
52.31
UniProt:
O15131
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15131
NP_002260.2
536
60349
S221
L
L
E
L
L
T
N
S
N
R
L
T
T
T
R
Chimpanzee
Pan troglodytes
XP_518711
559
63053
S244
L
L
E
L
L
T
N
S
N
R
L
T
T
T
R
Rhesus Macaque
Macaca mulatta
XP_001102290
566
62946
S251
L
L
T
L
L
T
K
S
T
R
L
T
M
T
R
Dog
Lupus familis
XP_541211
536
60241
S221
L
L
E
L
L
T
N
S
N
R
L
T
T
T
R
Cat
Felis silvestris
Mouse
Mus musculus
O35345
536
59946
S221
L
L
T
L
L
T
K
S
T
R
L
T
M
T
R
Rat
Rattus norvegicus
Q56R16
536
60281
S221
L
L
E
L
L
T
N
S
N
R
L
T
T
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518163
554
62067
S239
L
L
E
L
L
T
N
S
N
R
L
T
T
T
R
Chicken
Gallus gallus
Q5ZML1
538
60176
Q223
L
L
Q
L
L
S
K
Q
N
R
I
T
M
T
R
Frog
Xenopus laevis
P52170
522
57670
Q213
L
L
A
L
V
N
P
Q
T
P
L
G
Y
L
R
Zebra Danio
Brachydanio rerio
Q503E9
536
59774
S221
L
Q
Q
L
L
A
K
S
N
R
L
T
T
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52295
522
57803
E209
I
L
P
L
I
N
N
E
T
P
L
S
F
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19969
514
56144
E204
L
L
Q
F
I
N
P
E
I
P
I
G
F
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96321
532
58626
E211
P
L
L
N
Q
L
N
E
H
A
K
L
S
M
L
Baker's Yeast
Sacchar. cerevisiae
Q02821
542
60423
S226
P
I
L
G
L
F
N
S
N
K
P
S
L
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
79.8
99
N.A.
84.5
94
N.A.
93.1
79
45.1
89.3
N.A.
47.7
N.A.
42.5
N.A.
Protein Similarity:
100
95.7
86
99.8
N.A.
91
97.3
N.A.
95.1
89.2
63.2
94.4
N.A.
63.4
N.A.
60
N.A.
P-Site Identity:
100
100
73.3
100
N.A.
73.3
100
N.A.
100
60
33.3
73.3
N.A.
33.3
N.A.
20
N.A.
P-Site Similarity:
100
100
73.3
100
N.A.
73.3
100
N.A.
100
80
40
80
N.A.
53.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
53.5
50.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.2
67.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
36
0
0
0
0
22
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
8
0
0
0
0
0
0
15
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
15
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
15
0
0
0
8
0
15
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
29
0
0
8
8
0
0
0
0
% K
% Leu:
79
86
15
79
72
8
0
0
0
0
72
8
8
22
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
22
8
0
% M
% Asn:
0
0
0
8
0
22
58
0
58
0
0
0
0
0
0
% N
% Pro:
15
0
8
0
0
0
15
0
0
22
8
0
0
0
0
% P
% Gln:
0
8
22
0
8
0
0
15
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
65
0
0
0
0
93
% R
% Ser:
0
0
0
0
0
8
0
65
0
0
0
15
8
0
0
% S
% Thr:
0
0
15
0
0
50
0
0
29
0
0
65
43
65
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _