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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNA5
All Species:
30.61
Human Site:
S456
Identified Species:
51.79
UniProt:
O15131
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15131
NP_002260.2
536
60349
S456
L
R
L
G
E
Q
E
S
K
Q
N
G
I
G
I
Chimpanzee
Pan troglodytes
XP_518711
559
63053
S479
L
R
L
G
E
Q
E
S
K
Q
N
G
I
G
I
Rhesus Macaque
Macaca mulatta
XP_001102290
566
62946
G486
L
R
L
G
E
Q
E
G
K
R
S
G
S
G
V
Dog
Lupus familis
XP_541211
536
60241
S456
L
R
L
G
E
Q
E
S
K
Q
N
G
I
G
I
Cat
Felis silvestris
Mouse
Mus musculus
O35345
536
59946
S456
L
R
L
G
E
Q
E
S
K
R
S
G
S
G
V
Rat
Rattus norvegicus
Q56R16
536
60281
S456
L
R
L
G
E
R
E
S
K
Q
N
G
V
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518163
554
62067
S474
L
R
L
G
E
Q
E
S
K
Q
G
G
M
G
I
Chicken
Gallus gallus
Q5ZML1
538
60176
S458
L
R
L
G
E
Q
E
S
K
R
S
G
A
G
I
Frog
Xenopus laevis
P52170
522
57670
A443
A
I
S
N
I
F
L
A
A
E
K
L
G
E
Q
Zebra Danio
Brachydanio rerio
Q503E9
536
59774
S456
L
R
L
G
E
Q
E
S
K
Q
N
G
T
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52295
522
57803
L440
G
L
S
N
L
F
A
L
A
E
K
L
G
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19969
514
56144
A439
L
K
M
A
G
E
A
A
E
Q
V
T
S
E
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96321
532
58626
N448
K
V
G
E
A
E
K
N
L
G
H
T
G
D
M
Baker's Yeast
Sacchar. cerevisiae
Q02821
542
60423
K463
L
K
M
G
E
A
D
K
E
A
R
G
L
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
79.8
99
N.A.
84.5
94
N.A.
93.1
79
45.1
89.3
N.A.
47.7
N.A.
42.5
N.A.
Protein Similarity:
100
95.7
86
99.8
N.A.
91
97.3
N.A.
95.1
89.2
63.2
94.4
N.A.
63.4
N.A.
60
N.A.
P-Site Identity:
100
100
66.6
100
N.A.
73.3
86.6
N.A.
86.6
80
0
93.3
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
93.3
100
N.A.
93.3
93.3
13.3
93.3
N.A.
13.3
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
53.5
50.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.2
67.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
8
15
15
15
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
8
72
15
65
0
15
15
0
0
0
15
0
% E
% Phe:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
72
8
0
0
8
0
8
8
72
22
72
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
0
0
0
22
0
65
% I
% Lys:
8
15
0
0
0
0
8
8
65
0
15
0
0
0
0
% K
% Leu:
79
8
65
0
8
0
8
8
8
0
0
15
8
0
0
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
15
0
0
0
8
0
0
36
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
58
0
0
0
50
0
0
0
0
8
% Q
% Arg:
0
65
0
0
0
8
0
0
0
22
8
0
0
0
0
% R
% Ser:
0
0
15
0
0
0
0
58
0
0
22
0
22
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
15
8
0
8
% T
% Val:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _