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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNA5 All Species: 38.48
Human Site: Y308 Identified Species: 65.13
UniProt: O15131 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15131 NP_002260.2 536 60349 Y308 E L L M H N D Y K V V S P A L
Chimpanzee Pan troglodytes XP_518711 559 63053 Y331 E L L M H N D Y K V V S P A L
Rhesus Macaque Macaca mulatta XP_001102290 566 62946 Y338 E L L M H N D Y K V A S P A L
Dog Lupus familis XP_541211 536 60241 Y308 E L L M H N D Y K V V S P A L
Cat Felis silvestris
Mouse Mus musculus O35345 536 59946 Y308 E L L M H N D Y K V A S P A L
Rat Rattus norvegicus Q56R16 536 60281 Y308 E L L M H N D Y K V V S P A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518163 554 62067 Y326 E L L M H N D Y K V V S P A L
Chicken Gallus gallus Q5ZML1 538 60176 Y310 E L L M H N D Y K V V S P A L
Frog Xenopus laevis P52170 522 57670 L300 Q L M Y S P E L S I V T P S L
Zebra Danio Brachydanio rerio Q503E9 536 59774 Y308 E L L M H S D Y K V V S P A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52295 522 57803 P296 K L L Q M D E P S I I V P A L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19969 514 56144 V291 P L L G H V D V K V Q T A A L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96321 532 58626 P298 E L L L H H S P S V L I P A L
Baker's Yeast Sacchar. cerevisiae Q02821 542 60423 T313 E L L S H E S T L V Q T P A L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.5 79.8 99 N.A. 84.5 94 N.A. 93.1 79 45.1 89.3 N.A. 47.7 N.A. 42.5 N.A.
Protein Similarity: 100 95.7 86 99.8 N.A. 91 97.3 N.A. 95.1 89.2 63.2 94.4 N.A. 63.4 N.A. 60 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 93.3 100 N.A. 100 100 26.6 93.3 N.A. 33.3 N.A. 53.3 N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 100 N.A. 100 100 66.6 100 N.A. 66.6 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 53.5 50.3 N.A.
Protein Similarity: N.A. N.A. N.A. 69.2 67.9 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 15 0 8 93 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 72 0 0 0 0 0 0 0 0 % D
% Glu: 79 0 0 0 0 8 15 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 86 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 15 8 8 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 72 0 0 0 0 0 0 % K
% Leu: 0 100 93 8 0 0 0 8 8 0 8 0 0 0 100 % L
% Met: 0 0 8 65 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 58 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 8 0 15 0 0 0 0 93 0 0 % P
% Gln: 8 0 0 8 0 0 0 0 0 0 15 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 8 8 8 15 0 22 0 0 65 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 22 0 0 0 % T
% Val: 0 0 0 0 0 8 0 8 0 86 58 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 65 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _