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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNA5 All Species: 16.06
Human Site: Y51 Identified Species: 27.18
UniProt: O15131 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15131 NP_002260.2 536 60349 Y51 L F K R R N V Y L P R N D E S
Chimpanzee Pan troglodytes XP_518711 559 63053 S74 L F K R R N V S L P R N D E S
Rhesus Macaque Macaca mulatta XP_001102290 566 62946 R81 E Q Q L F K R R N V E L I N E
Dog Lupus familis XP_541211 536 60241 S51 L F K R R N V S L P R N D E S
Cat Felis silvestris
Mouse Mus musculus O35345 536 59946 R51 E Q Q L F K R R N V E L I N E
Rat Rattus norvegicus Q56R16 536 60281 S51 L F K R R N V S L P R N D D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518163 554 62067 C69 L F K R R N V C L P G N D E S
Chicken Gallus gallus Q5ZML1 538 60176 A53 K R R N V A T A E E E A E E E
Frog Xenopus laevis P52170 522 57670 I44 K A K K D E Q I L K R R N V C
Zebra Danio Brachydanio rerio Q503E9 536 59774 S51 L F K R R N V S L P P G D E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52295 522 57803 E40 E L R K S K K E D Q M F K R R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19969 514 56144 E36 I R K D K R E E A I S K R R N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96321 532 58626 E43 I R K S K R E E S L M K K R R
Baker's Yeast Sacchar. cerevisiae Q02821 542 60423 F58 A L A K R R N F I P P T D G A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.5 79.8 99 N.A. 84.5 94 N.A. 93.1 79 45.1 89.3 N.A. 47.7 N.A. 42.5 N.A.
Protein Similarity: 100 95.7 86 99.8 N.A. 91 97.3 N.A. 95.1 89.2 63.2 94.4 N.A. 63.4 N.A. 60 N.A.
P-Site Identity: 100 93.3 0 93.3 N.A. 0 80 N.A. 86.6 6.6 20 80 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 6.6 93.3 N.A. 6.6 86.6 N.A. 86.6 20 33.3 80 N.A. 13.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 53.5 50.3 N.A.
Protein Similarity: N.A. N.A. N.A. 69.2 67.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 0 8 0 8 8 0 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 15 % C
% Asp: 0 0 0 8 8 0 0 0 8 0 0 0 50 8 0 % D
% Glu: 22 0 0 0 0 8 15 22 8 8 22 0 8 43 22 % E
% Phe: 0 43 0 0 15 0 0 8 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 0 0 0 0 8 8 8 0 0 15 0 0 % I
% Lys: 15 0 65 22 15 22 8 0 0 8 0 15 15 0 0 % K
% Leu: 43 15 0 15 0 0 0 0 50 8 0 15 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % M
% Asn: 0 0 0 8 0 43 8 0 15 0 0 36 8 15 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 50 15 0 0 0 0 % P
% Gln: 0 15 15 0 0 0 8 0 0 8 0 0 0 0 0 % Q
% Arg: 0 22 15 43 50 22 15 15 0 0 36 8 8 22 15 % R
% Ser: 0 0 0 8 8 0 0 29 8 0 8 0 0 0 36 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % T
% Val: 0 0 0 0 8 0 43 0 0 15 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _