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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUSK
All Species:
16.97
Human Site:
S669
Identified Species:
31.11
UniProt:
O15146
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15146
NP_005583.1
869
97056
S669
D
L
N
E
F
L
R
S
M
S
P
H
T
V
C
Chimpanzee
Pan troglodytes
Q5IS37
825
92786
L625
E
Y
M
K
H
G
D
L
N
K
F
L
R
A
H
Rhesus Macaque
Macaca mulatta
XP_001106626
869
96940
S669
D
L
N
E
F
L
R
S
M
S
P
H
T
V
C
Dog
Lupus familis
XP_538784
992
109405
S669
D
L
N
E
F
L
R
S
R
S
P
H
A
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61006
868
96674
S668
D
L
N
E
F
L
R
S
M
S
P
H
T
V
C
Rat
Rattus norvegicus
Q62838
868
96804
S668
D
L
N
E
F
L
R
S
M
S
P
H
T
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508938
874
97520
N674
D
L
N
E
F
L
R
N
M
S
P
R
T
V
C
Chicken
Gallus gallus
Q8AXY6
947
105570
D749
D
L
N
E
Y
L
R
D
R
S
P
R
N
L
C
Frog
Xenopus laevis
Q9PVZ4
1362
153727
K1084
R
L
L
G
V
V
S
K
G
Q
P
T
L
V
I
Zebra Danio
Brachydanio rerio
NP_001004503
941
106241
R740
D
L
N
E
F
L
R
R
R
C
A
T
Q
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K3
724
81818
F532
A
P
G
D
L
S
E
F
L
R
A
C
S
P
Y
Honey Bee
Apis mellifera
XP_391863
648
74770
E457
N
Y
I
I
R
S
L
E
K
D
E
H
F
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26614
972
110463
Q712
N
L
L
G
C
C
T
Q
E
G
P
P
Y
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.7
99.1
80.9
N.A.
93
93.4
N.A.
82.7
71.3
20.1
59
N.A.
29.9
33.5
N.A.
22.5
Protein Similarity:
100
42.9
99.5
82.5
N.A.
96.4
96.8
N.A.
90.2
80.9
35.5
70.7
N.A.
44.9
48.3
N.A.
40
P-Site Identity:
100
0
100
73.3
N.A.
100
100
N.A.
86.6
60
20
46.6
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
13.3
100
73.3
N.A.
100
100
N.A.
93.3
73.3
26.6
46.6
N.A.
20
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
16
0
8
16
0
% A
% Cys:
0
0
0
0
8
8
0
0
0
8
0
8
0
0
47
% C
% Asp:
62
0
0
8
0
0
8
8
0
8
0
0
0
0
8
% D
% Glu:
8
0
0
62
0
0
8
8
8
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
54
0
0
8
0
0
8
0
8
0
0
% F
% Gly:
0
0
8
16
0
8
0
0
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
47
0
0
8
% H
% Ile:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
0
0
0
8
0
0
0
8
8
8
0
0
0
0
0
% K
% Leu:
0
77
16
0
8
62
8
8
8
0
0
8
8
8
0
% L
% Met:
0
0
8
0
0
0
0
0
39
0
0
0
0
0
0
% M
% Asn:
16
0
62
0
0
0
0
8
8
0
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
70
8
0
8
16
% P
% Gln:
0
0
0
0
0
0
0
8
0
8
0
0
8
8
0
% Q
% Arg:
8
0
0
0
8
0
62
8
24
8
0
16
8
0
0
% R
% Ser:
0
0
0
0
0
16
8
39
0
54
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
16
39
8
0
% T
% Val:
0
0
0
0
8
8
0
0
0
0
0
0
0
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
0
8
0
0
0
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _