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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUSK
All Species:
13.03
Human Site:
S681
Identified Species:
23.89
UniProt:
O15146
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15146
NP_005583.1
869
97056
S681
T
V
C
S
L
S
H
S
D
L
S
M
R
A
Q
Chimpanzee
Pan troglodytes
Q5IS37
825
92786
M637
R
A
H
G
P
D
A
M
I
L
V
D
G
Q
P
Rhesus Macaque
Macaca mulatta
XP_001106626
869
96940
S681
T
V
C
S
L
S
H
S
D
L
S
M
R
A
Q
Dog
Lupus familis
XP_538784
992
109405
P681
A
A
P
R
S
P
G
P
P
P
A
P
G
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61006
868
96674
S680
T
V
C
S
L
S
H
S
D
L
S
T
R
A
R
Rat
Rattus norvegicus
Q62838
868
96804
S680
T
V
C
S
L
S
H
S
D
L
S
T
R
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508938
874
97520
G686
T
V
C
S
L
S
H
G
N
L
V
P
R
M
R
Chicken
Gallus gallus
Q8AXY6
947
105570
G761
N
L
C
S
L
V
Q
G
G
L
E
A
R
A
C
Frog
Xenopus laevis
Q9PVZ4
1362
153727
A1096
L
V
I
M
E
L
M
A
H
G
D
L
K
S
Y
Zebra Danio
Brachydanio rerio
NP_001004503
941
106241
D752
Q
Q
P
S
L
S
R
D
T
L
T
S
S
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K3
724
81818
A544
S
P
Y
A
T
H
Q
A
P
T
Q
D
R
L
Q
Honey Bee
Apis mellifera
XP_391863
648
74770
H469
F
T
D
S
R
L
S
H
M
D
L
I
N
I
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26614
972
110463
H724
Y
V
I
V
E
F
A
H
H
G
N
L
R
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.7
99.1
80.9
N.A.
93
93.4
N.A.
82.7
71.3
20.1
59
N.A.
29.9
33.5
N.A.
22.5
Protein Similarity:
100
42.9
99.5
82.5
N.A.
96.4
96.8
N.A.
90.2
80.9
35.5
70.7
N.A.
44.9
48.3
N.A.
40
P-Site Identity:
100
6.6
100
0
N.A.
86.6
86.6
N.A.
60
40
6.6
26.6
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
6.6
100
6.6
N.A.
93.3
93.3
N.A.
73.3
46.6
33.3
40
N.A.
33.3
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
8
0
0
16
16
0
0
8
8
0
39
8
% A
% Cys:
0
0
47
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
8
0
0
8
0
8
31
8
8
16
0
8
0
% D
% Glu:
0
0
0
0
16
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
8
16
8
16
0
0
16
0
0
% G
% His:
0
0
8
0
0
8
39
16
16
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
0
0
0
8
0
0
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
8
8
0
0
54
16
0
0
0
62
8
16
0
8
8
% L
% Met:
0
0
0
8
0
0
8
8
8
0
0
16
0
8
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
8
0
8
0
0
% N
% Pro:
0
8
16
0
8
8
0
8
16
8
0
16
0
0
16
% P
% Gln:
8
8
0
0
0
0
16
0
0
0
8
0
0
8
24
% Q
% Arg:
8
0
0
8
8
0
8
0
0
0
0
0
62
8
24
% R
% Ser:
8
0
0
62
8
47
8
31
0
0
31
8
8
16
0
% S
% Thr:
39
8
0
0
8
0
0
0
8
8
8
16
0
0
0
% T
% Val:
0
54
0
8
0
8
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _