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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MUSK All Species: 20.61
Human Site: S691 Identified Species: 37.78
UniProt: O15146 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15146 NP_005583.1 869 97056 S691 S M R A Q V S S P G P P P L S
Chimpanzee Pan troglodytes Q5IS37 825 92786 A647 V D G Q P R Q A K G E L G L S
Rhesus Macaque Macaca mulatta XP_001106626 869 96940 S691 S M R A Q V S S P G P P P L S
Dog Lupus familis XP_538784 992 109405 P691 A P G R P P P P P P P P P L S
Cat Felis silvestris
Mouse Mus musculus Q61006 868 96674 S690 S T R A R V S S P G P P P L S
Rat Rattus norvegicus Q62838 868 96804 S690 S T R A R V S S P G P P P L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508938 874 97520 S696 V P R M R I S S P G P P P L C
Chicken Gallus gallus Q8AXY6 947 105570 N771 E A R A C L L N P L A L C C T
Frog Xenopus laevis Q9PVZ4 1362 153727 S1106 D L K S Y L R S L R P D A E N
Zebra Danio Brachydanio rerio NP_001004503 941 106241 E762 T S S S L V S E P E R Y P P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V6K3 724 81818 E554 Q D R L Q L N E L H L L Q M A
Honey Bee Apis mellifera XP_391863 648 74770 V479 L I N I A L Q V A S G M V Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26614 972 110463 S734 N L R D F L R S R R P P E E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.7 99.1 80.9 N.A. 93 93.4 N.A. 82.7 71.3 20.1 59 N.A. 29.9 33.5 N.A. 22.5
Protein Similarity: 100 42.9 99.5 82.5 N.A. 96.4 96.8 N.A. 90.2 80.9 35.5 70.7 N.A. 44.9 48.3 N.A. 40
P-Site Identity: 100 20 100 40 N.A. 86.6 86.6 N.A. 60 20 13.3 26.6 N.A. 13.3 0 N.A. 26.6
P-Site Similarity: 100 26.6 100 46.6 N.A. 93.3 93.3 N.A. 73.3 40 46.6 40 N.A. 40 13.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 39 8 0 0 8 8 0 8 0 8 0 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 8 8 8 % C
% Asp: 8 16 0 8 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 16 0 8 8 0 8 16 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 16 0 0 0 0 0 0 47 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % K
% Leu: 8 16 0 8 8 39 8 0 16 8 8 24 0 54 16 % L
% Met: 0 16 0 8 0 0 0 0 0 0 0 8 0 8 0 % M
% Asn: 8 0 8 0 0 0 8 8 0 0 0 0 0 0 8 % N
% Pro: 0 16 0 0 16 8 8 8 62 8 62 54 54 8 0 % P
% Gln: 8 0 0 8 24 0 16 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 62 8 24 8 16 0 8 16 8 0 0 0 0 % R
% Ser: 31 8 8 16 0 0 47 54 0 8 0 0 0 0 47 % S
% Thr: 8 16 0 0 0 0 0 0 0 0 0 0 0 0 8 % T
% Val: 16 0 0 0 0 39 0 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 8 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _