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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUSK
All Species:
28.18
Human Site:
T535
Identified Species:
51.67
UniProt:
O15146
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15146
NP_005583.1
869
97056
T535
K
R
E
S
A
A
V
T
L
T
T
L
P
S
E
Chimpanzee
Pan troglodytes
Q5IS37
825
92786
N522
Q
Y
F
R
Q
G
H
N
C
H
K
P
D
T
Y
Rhesus Macaque
Macaca mulatta
XP_001106626
869
96940
T535
K
R
E
S
A
A
V
T
L
T
T
L
P
S
E
Dog
Lupus familis
XP_538784
992
109405
T535
K
R
E
S
A
A
V
T
L
T
T
L
P
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61006
868
96674
T534
K
R
E
S
T
A
V
T
L
T
T
L
P
S
E
Rat
Rattus norvegicus
Q62838
868
96804
T534
K
R
E
S
A
A
V
T
L
T
T
L
P
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508938
874
97520
T540
K
R
E
S
A
T
P
T
L
T
T
L
P
S
E
Chicken
Gallus gallus
Q8AXY6
947
105570
T615
K
R
E
S
E
T
P
T
L
T
T
L
P
S
E
Frog
Xenopus laevis
Q9PVZ4
1362
153727
V972
I
V
L
V
Y
C
V
V
Q
K
K
K
D
A
E
Zebra Danio
Brachydanio rerio
NP_001004503
941
106241
T606
S
R
V
L
E
T
P
T
L
T
T
L
P
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K3
724
81818
E432
T
K
P
N
A
R
L
E
K
L
E
Y
P
R
G
Honey Bee
Apis mellifera
XP_391863
648
74770
L357
N
I
I
Y
V
R
D
L
G
Q
G
A
F
G
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26614
972
110463
Q595
G
P
K
H
L
Y
R
Q
T
S
V
D
S
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.7
99.1
80.9
N.A.
93
93.4
N.A.
82.7
71.3
20.1
59
N.A.
29.9
33.5
N.A.
22.5
Protein Similarity:
100
42.9
99.5
82.5
N.A.
96.4
96.8
N.A.
90.2
80.9
35.5
70.7
N.A.
44.9
48.3
N.A.
40
P-Site Identity:
100
0
100
100
N.A.
93.3
100
N.A.
86.6
80
13.3
60
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
100
N.A.
86.6
80
20
60
N.A.
33.3
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
47
39
0
0
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
8
16
0
0
% D
% Glu:
0
0
54
0
16
0
0
8
0
0
8
0
0
0
70
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
8
0
8
0
0
8
8
% G
% His:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
54
8
8
0
0
0
0
0
8
8
16
8
0
0
0
% K
% Leu:
0
0
8
8
8
0
8
8
62
8
0
62
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
0
0
24
0
0
0
0
8
70
0
0
% P
% Gln:
8
0
0
0
8
0
0
8
8
8
0
0
0
0
8
% Q
% Arg:
0
62
0
8
0
16
8
0
0
0
0
0
0
8
8
% R
% Ser:
8
0
0
54
0
0
0
0
0
8
0
0
8
62
0
% S
% Thr:
8
0
0
0
8
24
0
62
8
62
62
0
0
16
0
% T
% Val:
0
8
8
8
8
0
47
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
8
8
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _