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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUSK
All Species:
17.58
Human Site:
Y516
Identified Species:
32.22
UniProt:
O15146
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15146
NP_005583.1
869
97056
Y516
L
L
T
I
T
T
L
Y
C
C
R
R
R
K
Q
Chimpanzee
Pan troglodytes
Q5IS37
825
92786
I503
A
G
P
D
T
V
V
I
G
M
T
R
I
P
V
Rhesus Macaque
Macaca mulatta
XP_001106626
869
96940
Y516
L
L
T
I
T
T
L
Y
C
C
R
R
R
K
Q
Dog
Lupus familis
XP_538784
992
109405
Y516
L
L
T
V
T
T
F
Y
C
C
R
R
R
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61006
868
96674
Y515
L
L
T
I
A
T
L
Y
C
C
R
R
R
K
E
Rat
Rattus norvegicus
Q62838
868
96804
Y515
L
L
T
I
T
T
L
Y
C
C
R
R
R
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508938
874
97520
L521
G
L
F
T
I
T
T
L
V
C
C
R
R
R
K
Chicken
Gallus gallus
Q8AXY6
947
105570
V596
I
L
G
I
I
T
L
V
C
C
R
R
R
K
Q
Frog
Xenopus laevis
Q9PVZ4
1362
153727
I953
H
S
N
I
V
K
I
I
T
G
P
I
I
A
V
Zebra Danio
Brachydanio rerio
NP_001004503
941
106241
C587
F
T
V
L
I
L
M
C
H
R
R
K
K
M
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K3
724
81818
L413
I
H
S
N
C
V
A
L
T
T
V
T
N
V
S
Honey Bee
Apis mellifera
XP_391863
648
74770
N338
H
K
T
S
A
Q
L
N
P
K
L
E
K
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26614
972
110463
R576
L
C
K
Q
T
Q
V
R
H
R
R
P
S
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.7
99.1
80.9
N.A.
93
93.4
N.A.
82.7
71.3
20.1
59
N.A.
29.9
33.5
N.A.
22.5
Protein Similarity:
100
42.9
99.5
82.5
N.A.
96.4
96.8
N.A.
90.2
80.9
35.5
70.7
N.A.
44.9
48.3
N.A.
40
P-Site Identity:
100
13.3
100
86.6
N.A.
86.6
86.6
N.A.
33.3
73.3
6.6
6.6
N.A.
0
13.3
N.A.
20
P-Site Similarity:
100
20
100
93.3
N.A.
93.3
100
N.A.
46.6
80
13.3
33.3
N.A.
13.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
16
0
8
0
0
0
0
0
0
8
0
% A
% Cys:
0
8
0
0
8
0
0
8
47
54
8
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
24
% E
% Phe:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
0
0
0
8
8
0
0
0
0
0
% G
% His:
16
8
0
0
0
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
16
0
0
47
24
0
8
16
0
0
0
8
16
0
0
% I
% Lys:
0
8
8
0
0
8
0
0
0
8
0
8
16
39
16
% K
% Leu:
47
54
0
8
0
8
47
16
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
0
0
8
0
% M
% Asn:
0
0
8
8
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
8
0
8
8
0
8
0
% P
% Gln:
0
0
0
8
0
16
0
0
0
0
0
0
0
0
31
% Q
% Arg:
0
0
0
0
0
0
0
8
0
16
62
62
54
16
0
% R
% Ser:
0
8
8
8
0
0
0
0
0
0
0
0
8
0
8
% S
% Thr:
0
8
47
8
47
54
8
0
16
8
8
8
0
0
0
% T
% Val:
0
0
8
8
8
16
16
8
8
0
8
0
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _