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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1C
All Species:
13.64
Human Site:
S254
Identified Species:
23.08
UniProt:
O15160
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15160
NP_004866.1
346
39250
S254
G
E
A
A
E
E
L
S
R
C
F
S
P
G
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096103
291
32936
I207
R
C
F
S
P
G
V
I
E
V
Q
E
V
Q
G
Dog
Lupus familis
XP_532147
346
39172
S254
G
D
A
A
E
E
L
S
R
C
F
S
P
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P52432
346
39057
S254
G
E
A
A
E
E
L
S
Q
C
F
S
P
G
V
Rat
Rattus norvegicus
NP_001008331
346
38999
S254
G
E
A
A
E
E
L
S
Q
C
F
S
P
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507416
346
39271
K254
G
E
M
A
E
K
L
K
D
C
F
S
P
G
V
Chicken
Gallus gallus
XP_419502
346
39361
Q254
D
E
A
A
E
T
L
Q
K
C
F
S
P
G
V
Frog
Xenopus laevis
NP_001085237
347
39341
Q255
G
E
L
A
D
K
L
Q
G
C
F
S
P
G
V
Zebra Danio
Brachydanio rerio
NP_956860
347
39135
K255
G
E
Q
A
E
R
L
K
R
C
F
S
P
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608885
333
38119
Q247
G
K
D
A
Y
L
L
Q
N
C
F
S
P
G
V
Honey Bee
Apis mellifera
XP_625072
347
39996
K252
G
E
M
A
D
R
L
K
N
C
F
S
I
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795508
335
37712
Q239
G
E
R
A
K
K
L
Q
Q
C
F
S
S
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39212
319
35557
K209
N
T
L
T
D
E
E
K
I
D
L
I
E
S
S
Baker's Yeast
Sacchar. cerevisiae
P07703
335
37668
Q248
G
E
S
A
R
R
F
Q
K
C
F
P
P
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.2
97.4
N.A.
93.3
94.5
N.A.
85.5
82.3
77.8
71.4
N.A.
51.1
51.2
N.A.
57.8
Protein Similarity:
100
N.A.
84
99.7
N.A.
97.9
98.2
N.A.
94.8
92.4
87.9
87.6
N.A.
69
72
N.A.
74.2
P-Site Identity:
100
N.A.
0
93.3
N.A.
93.3
93.3
N.A.
73.3
73.3
66.6
80
N.A.
60
60
N.A.
60
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
80
80
80
80
N.A.
66.6
66.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
43.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
36
86
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
86
0
0
0
0
0
% C
% Asp:
8
8
8
0
22
0
0
0
8
8
0
0
0
0
0
% D
% Glu:
0
72
0
0
50
36
8
0
8
0
0
8
8
0
0
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
86
0
0
0
0
% F
% Gly:
79
0
0
0
0
8
0
0
8
0
0
0
0
86
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
0
0
8
8
0
0
% I
% Lys:
0
8
0
0
8
22
0
29
15
0
0
0
0
0
0
% K
% Leu:
0
0
15
0
0
8
79
0
0
0
8
0
0
0
0
% L
% Met:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
8
72
0
0
% P
% Gln:
0
0
8
0
0
0
0
36
22
0
8
0
0
8
0
% Q
% Arg:
8
0
8
0
8
22
0
0
22
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
0
0
0
29
0
0
0
79
8
8
8
% S
% Thr:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
8
0
0
8
0
86
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _