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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1C
All Species:
1.05
Human Site:
S4
Identified Species:
1.78
UniProt:
O15160
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15160
NP_004866.1
346
39250
S4
_
_
_
_
M
A
A
S
Q
A
V
E
E
M
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096103
291
32936
N4
_
_
_
_
M
D
E
N
S
L
E
F
D
M
V
Dog
Lupus familis
XP_532147
346
39172
A4
_
_
_
_
M
A
A
A
Q
A
V
Q
E
M
R
Cat
Felis silvestris
Mouse
Mus musculus
P52432
346
39057
A4
_
_
_
_
M
A
A
A
Q
A
V
E
E
M
R
Rat
Rattus norvegicus
NP_001008331
346
38999
A4
_
_
_
_
M
A
A
A
Q
A
V
E
E
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507416
346
39271
A4
_
_
_
_
M
A
A
A
E
A
V
R
E
M
R
Chicken
Gallus gallus
XP_419502
346
39361
K4
_
_
_
_
M
A
A
K
R
S
M
D
E
L
R
Frog
Xenopus laevis
NP_001085237
347
39341
P4
_
_
_
_
M
A
T
P
G
S
V
Q
L
I
R
Zebra Danio
Brachydanio rerio
NP_956860
347
39135
M5
_
_
_
M
A
A
P
M
S
N
V
D
E
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608885
333
38119
N5
_
_
_
M
A
S
K
N
R
K
E
P
L
L
Y
Honey Bee
Apis mellifera
XP_625072
347
39996
I4
_
_
_
_
M
E
E
I
R
K
S
R
V
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795508
335
37712
I5
_
_
_
M
H
I
P
I
R
N
T
V
Q
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39212
319
35557
Y6
_
_
M
D
G
V
T
Y
Q
R
F
P
T
V
K
Baker's Yeast
Sacchar. cerevisiae
P07703
335
37668
I4
_
_
_
_
M
S
N
I
V
G
I
E
Y
N
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.2
97.4
N.A.
93.3
94.5
N.A.
85.5
82.3
77.8
71.4
N.A.
51.1
51.2
N.A.
57.8
Protein Similarity:
100
N.A.
84
99.7
N.A.
97.9
98.2
N.A.
94.8
92.4
87.9
87.6
N.A.
69
72
N.A.
74.2
P-Site Identity:
100
N.A.
18.1
81.8
N.A.
90.9
90.9
N.A.
72.7
45.4
36.3
33.3
N.A.
0
9
N.A.
0
P-Site Similarity:
100
N.A.
36.3
100
N.A.
100
100
N.A.
90.9
90.9
63.6
50
N.A.
33.3
27.2
N.A.
25
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
43.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
7.6
27.2
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
23
45.4
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
58
43
29
0
36
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
0
0
0
0
15
8
0
0
% D
% Glu:
0
0
0
0
0
8
15
0
8
0
15
29
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
8
8
0
0
0
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
22
0
0
8
0
0
22
0
% I
% Lys:
0
0
0
0
0
0
8
8
0
15
0
0
0
0
15
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
0
15
15
8
% L
% Met:
0
0
8
22
72
0
0
8
0
0
8
0
0
43
0
% M
% Asn:
0
0
0
0
0
0
8
15
0
15
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
15
8
0
0
0
15
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
36
0
0
15
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
29
8
0
15
0
0
65
% R
% Ser:
0
0
0
0
0
15
0
8
15
15
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
15
0
0
0
8
0
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
8
0
50
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
8
% Y
% Spaces:
100
100
93
72
0
0
0
0
0
0
0
0
0
0
0
% _