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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1C
All Species:
16.36
Human Site:
T189
Identified Species:
27.69
UniProt:
O15160
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15160
NP_004866.1
346
39250
T189
A
D
L
F
P
E
G
T
I
R
P
V
H
D
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096103
291
32936
I163
L
M
H
C
V
K
G
I
G
K
D
H
A
K
F
Dog
Lupus familis
XP_532147
346
39172
T189
A
D
L
F
P
E
G
T
I
R
P
V
H
D
D
Cat
Felis silvestris
Mouse
Mus musculus
P52432
346
39057
T189
A
D
V
F
P
E
G
T
I
R
P
V
H
D
D
Rat
Rattus norvegicus
NP_001008331
346
38999
T189
A
D
V
F
P
E
G
T
V
R
P
V
H
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507416
346
39271
A189
A
D
L
F
P
E
G
A
I
R
P
V
H
D
D
Chicken
Gallus gallus
XP_419502
346
39361
D189
T
D
L
F
P
D
A
D
F
R
P
V
H
D
D
Frog
Xenopus laevis
NP_001085237
347
39341
D189
V
D
L
F
P
E
T
D
P
P
R
P
V
H
K
Zebra Danio
Brachydanio rerio
NP_956860
347
39135
K190
A
D
V
F
A
D
A
K
I
G
P
V
H
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608885
333
38119
A182
A
Q
I
Y
S
E
S
A
V
N
C
I
H
D
D
Honey Bee
Apis mellifera
XP_625072
347
39996
T185
A
E
L
Y
P
R
G
T
E
Q
L
S
V
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795508
335
37712
A174
E
E
T
Y
G
P
K
A
F
A
P
V
N
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39212
319
35557
K164
L
R
R
G
Q
E
L
K
L
K
A
L
A
R
K
Baker's Yeast
Sacchar. cerevisiae
P07703
335
37668
P183
S
T
T
F
A
D
C
P
V
V
P
A
D
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.2
97.4
N.A.
93.3
94.5
N.A.
85.5
82.3
77.8
71.4
N.A.
51.1
51.2
N.A.
57.8
Protein Similarity:
100
N.A.
84
99.7
N.A.
97.9
98.2
N.A.
94.8
92.4
87.9
87.6
N.A.
69
72
N.A.
74.2
P-Site Identity:
100
N.A.
6.6
100
N.A.
93.3
86.6
N.A.
93.3
66.6
33.3
53.3
N.A.
33.3
33.3
N.A.
20
P-Site Similarity:
100
N.A.
20
100
N.A.
100
100
N.A.
93.3
73.3
33.3
66.6
N.A.
60
60
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
43.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
0
0
15
0
15
22
0
8
8
8
15
0
0
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% C
% Asp:
0
58
0
0
0
22
0
15
0
0
8
0
8
50
72
% D
% Glu:
8
15
0
0
0
58
0
0
8
0
0
0
0
0
8
% E
% Phe:
0
0
0
65
0
0
0
0
15
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
8
0
50
0
8
8
0
0
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
58
8
0
% H
% Ile:
0
0
8
0
0
0
0
8
36
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
8
8
15
0
15
0
0
0
15
15
% K
% Leu:
15
0
43
0
0
0
8
0
8
0
8
8
0
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
58
8
0
8
8
8
65
8
0
8
0
% P
% Gln:
0
8
0
0
8
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
8
8
0
0
8
0
0
0
43
8
0
0
8
0
% R
% Ser:
8
0
0
0
8
0
8
0
0
0
0
8
0
0
0
% S
% Thr:
8
8
15
0
0
0
8
36
0
0
0
0
0
0
0
% T
% Val:
8
0
22
0
8
0
0
0
22
8
0
58
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _