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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1C
All Species:
36.06
Human Site:
Y124
Identified Species:
61.03
UniProt:
O15160
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15160
NP_004866.1
346
39250
Y124
A
D
P
R
L
F
E
Y
R
N
Q
G
D
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096103
291
32936
A98
C
T
R
N
P
H
A
A
K
D
S
S
D
P
N
Dog
Lupus familis
XP_532147
346
39172
Y124
A
D
P
R
L
F
E
Y
R
N
Q
G
D
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P52432
346
39057
Y124
A
D
P
R
L
F
E
Y
R
N
Q
G
E
E
E
Rat
Rattus norvegicus
NP_001008331
346
38999
Y124
A
D
P
R
L
F
E
Y
R
N
P
G
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507416
346
39271
Y124
A
D
P
R
L
F
E
Y
R
N
Q
G
D
E
E
Chicken
Gallus gallus
XP_419502
346
39361
Y124
A
D
P
R
L
F
E
Y
R
N
Q
G
D
E
E
Frog
Xenopus laevis
NP_001085237
347
39341
Y124
A
D
P
R
L
F
E
Y
R
S
A
D
D
A
E
Zebra Danio
Brachydanio rerio
NP_956860
347
39135
Y125
A
D
P
R
L
F
E
Y
R
N
S
E
D
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608885
333
38119
R117
D
P
R
L
F
A
Y
R
T
E
E
S
T
E
A
Honey Bee
Apis mellifera
XP_625072
347
39996
S120
R
L
F
E
Y
P
S
S
T
A
K
D
Q
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795508
335
37712
Y109
A
D
P
R
I
F
E
Y
R
E
E
G
D
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39212
319
35557
C99
D
C
N
G
D
E
H
C
E
F
C
S
V
E
F
Baker's Yeast
Sacchar. cerevisiae
P07703
335
37668
S118
D
M
L
T
W
V
D
S
N
L
P
D
D
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.2
97.4
N.A.
93.3
94.5
N.A.
85.5
82.3
77.8
71.4
N.A.
51.1
51.2
N.A.
57.8
Protein Similarity:
100
N.A.
84
99.7
N.A.
97.9
98.2
N.A.
94.8
92.4
87.9
87.6
N.A.
69
72
N.A.
74.2
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
93.3
86.6
N.A.
100
100
73.3
80
N.A.
6.6
6.6
N.A.
73.3
P-Site Similarity:
100
N.A.
20
100
N.A.
100
93.3
N.A.
100
100
80
86.6
N.A.
13.3
20
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
43.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
65
0
0
0
0
8
8
8
0
8
8
0
0
8
8
% A
% Cys:
8
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
22
65
0
0
8
0
8
0
0
8
0
22
65
15
0
% D
% Glu:
0
0
0
8
0
8
65
0
8
15
15
8
15
65
65
% E
% Phe:
0
0
8
0
8
65
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
50
0
0
0
% G
% His:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
8
% K
% Leu:
0
8
8
8
58
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
8
50
0
0
0
0
8
% N
% Pro:
0
8
65
0
8
8
0
0
0
0
15
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
36
0
8
8
0
% Q
% Arg:
8
0
15
65
0
0
0
8
65
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
15
0
8
15
22
0
0
0
% S
% Thr:
0
8
0
8
0
0
0
0
15
0
0
0
8
0
8
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _