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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1C
All Species:
44.85
Human Site:
Y163
Identified Species:
75.9
UniProt:
O15160
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15160
NP_004866.1
346
39250
Y163
S
S
D
P
N
E
L
Y
V
N
H
K
V
Y
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096103
291
32936
P137
F
P
E
G
T
I
R
P
V
H
D
D
I
L
I
Dog
Lupus familis
XP_532147
346
39172
Y163
S
S
D
P
N
E
L
Y
V
N
H
K
V
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
P52432
346
39057
Y163
S
S
D
P
N
E
L
Y
V
N
H
K
V
Y
T
Rat
Rattus norvegicus
NP_001008331
346
38999
Y163
S
S
D
P
N
E
L
Y
V
N
H
K
V
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507416
346
39271
Y163
S
S
D
P
N
Q
L
Y
L
N
H
K
V
Y
T
Chicken
Gallus gallus
XP_419502
346
39361
Y163
S
S
D
P
N
E
L
Y
F
N
H
K
V
Y
S
Frog
Xenopus laevis
NP_001085237
347
39341
Y163
C
S
D
P
N
E
L
Y
L
N
H
K
V
Y
T
Zebra Danio
Brachydanio rerio
NP_956860
347
39135
Y164
S
S
D
P
K
E
L
Y
L
N
H
M
I
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608885
333
38119
Y156
Q
S
N
F
D
D
I
Y
K
N
H
K
V
Y
S
Honey Bee
Apis mellifera
XP_625072
347
39996
Y159
S
R
R
T
N
D
M
Y
R
N
S
N
V
Y
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795508
335
37712
Y148
A
T
D
P
D
E
L
Y
K
N
A
K
V
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39212
319
35557
T138
T
V
T
P
V
D
F
T
S
N
S
S
T
S
D
Baker's Yeast
Sacchar. cerevisiae
P07703
335
37668
Y157
S
T
D
P
K
E
L
Y
N
N
A
H
V
Y
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.2
97.4
N.A.
93.3
94.5
N.A.
85.5
82.3
77.8
71.4
N.A.
51.1
51.2
N.A.
57.8
Protein Similarity:
100
N.A.
84
99.7
N.A.
97.9
98.2
N.A.
94.8
92.4
87.9
87.6
N.A.
69
72
N.A.
74.2
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
100
100
N.A.
86.6
86.6
86.6
66.6
N.A.
46.6
40
N.A.
60
P-Site Similarity:
100
N.A.
26.6
100
N.A.
100
100
N.A.
100
93.3
93.3
86.6
N.A.
80
60
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
43.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
15
0
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
72
0
15
22
0
0
0
0
8
8
0
0
8
% D
% Glu:
0
0
8
0
0
65
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
8
0
0
8
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
65
8
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
0
0
0
0
15
0
8
% I
% Lys:
0
0
0
0
15
0
0
0
15
0
0
65
0
0
0
% K
% Leu:
0
0
0
0
0
0
72
0
22
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
58
0
0
0
8
93
0
8
0
0
0
% N
% Pro:
0
8
0
79
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
0
0
0
8
0
8
0
0
0
0
0
0
% R
% Ser:
65
65
0
0
0
0
0
0
8
0
15
8
0
8
36
% S
% Thr:
8
15
8
8
8
0
0
8
0
0
0
0
8
8
43
% T
% Val:
0
8
0
0
8
0
0
0
36
0
0
0
79
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
0
0
79
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _