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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLSCR1
All Species:
24.55
Human Site:
T174
Identified Species:
49.09
UniProt:
O15162
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15162
NP_066928.1
318
35049
T174
N
M
G
Q
E
V
I
T
L
E
R
P
L
R
C
Chimpanzee
Pan troglodytes
XP_001135562
311
34199
T167
N
M
G
Q
E
V
I
T
L
E
R
P
L
R
C
Rhesus Macaque
Macaca mulatta
XP_001111222
318
35056
T174
N
M
G
R
E
V
I
T
L
E
R
P
L
R
C
Dog
Lupus familis
XP_854267
356
38604
T211
N
M
G
Q
E
V
I
T
L
E
R
P
L
R
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCW2
307
34062
T172
H
L
G
Q
E
V
M
T
L
E
R
P
L
R
C
Rat
Rattus norvegicus
P58195
335
36692
T191
N
M
G
R
E
V
M
T
L
E
R
P
L
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520623
294
32532
P160
E
V
I
S
L
Q
R
P
L
R
C
S
S
C
C
Chicken
Gallus gallus
XP_001231237
305
33647
R160
N
L
G
H
E
V
I
R
L
E
R
P
L
R
C
Frog
Xenopus laevis
Q92125
512
53295
S288
S
T
Y
Y
D
A
W
S
L
Y
N
A
M
K
G
Zebra Danio
Brachydanio rerio
NP_998031
314
34580
R168
N
M
D
R
E
V
I
R
L
I
R
P
Y
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648389
416
43675
H272
N
F
Q
Q
E
V
I
H
M
H
R
P
L
A
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001183154
279
30546
V160
V
S
S
P
P
G
T
V
I
G
Y
V
N
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
96.8
72.1
N.A.
66.3
71.9
N.A.
67.6
66
21
55.6
N.A.
44.9
N.A.
N.A.
55.3
Protein Similarity:
100
97.8
99
79.2
N.A.
76.7
80.5
N.A.
77
74.8
31.6
65.4
N.A.
53.6
N.A.
N.A.
66.6
P-Site Identity:
100
100
93.3
100
N.A.
80
86.6
N.A.
13.3
80
6.6
66.6
N.A.
60
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
86.6
40
73.3
N.A.
66.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
84
% C
% Asp:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
75
0
0
0
0
59
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
59
0
0
9
0
0
0
9
0
0
0
0
9
% G
% His:
9
0
0
9
0
0
0
9
0
9
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
59
0
9
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
0
17
0
0
9
0
0
0
84
0
0
0
67
0
0
% L
% Met:
0
50
0
0
0
0
17
0
9
0
0
0
9
0
0
% M
% Asn:
67
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% N
% Pro:
0
0
0
9
9
0
0
9
0
0
0
75
0
0
0
% P
% Gln:
0
0
9
42
0
9
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
25
0
0
9
17
0
9
75
0
0
67
0
% R
% Ser:
9
9
9
9
0
0
0
9
0
0
0
9
9
0
9
% S
% Thr:
0
9
0
0
0
0
9
50
0
0
0
0
0
0
0
% T
% Val:
9
9
0
0
0
75
0
9
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
0
9
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _