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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C18orf1 All Species: 22.12
Human Site: S153 Identified Species: 54.07
UniProt: O15165 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15165 NP_001003674.1 306 33900 S153 F I Q R D R F S R F Q P T Y P
Chimpanzee Pan troglodytes XP_001171389 313 34731 S160 F I Q R D R F S R F Q P T Y P
Rhesus Macaque Macaca mulatta XP_001091387 306 33741 S153 F I Q R D R F S R F Q P T Y P
Dog Lupus familis XP_541100 693 71465 S541 F L P R D R F S R F Q P T Y P
Cat Felis silvestris
Mouse Mus musculus Q8BWJ4 306 33838 S153 F I Q R D P F S R F Q P T Y P
Rat Rattus norvegicus XP_001053570 269 30036 V125 F Q P T Y P Y V Q H E I D L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505727 325 35569 S172 F M Q R D R F S R F Q P T Y P
Chicken Gallus gallus NP_001026184 201 22729 I57 Y P Y M Q H E I D L P P T I S
Frog Xenopus laevis NP_001108307 254 28627 I110 Y P Y I Q N E I D L P P T I S
Zebra Danio Brachydanio rerio XP_684772 424 46405 R266 F M Q H N R F R R F Q P T Y P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.4 97 32 N.A. 90.1 73.1 N.A. 65.2 56.5 56.2 46.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.7 98.3 36.6 N.A. 94.4 78.7 N.A. 75 61.7 66 58 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 93.3 13.3 N.A. 93.3 13.3 13.3 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 33.3 N.A. 100 20 20 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 60 0 0 0 20 0 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 20 0 0 0 10 0 0 0 0 % E
% Phe: 80 0 0 0 0 0 70 0 0 70 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 10 0 10 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 40 0 10 0 0 0 20 0 0 0 10 0 20 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 20 0 0 0 10 0 % L
% Met: 0 20 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 20 20 0 0 20 0 0 0 0 20 90 0 0 80 % P
% Gln: 0 10 60 0 20 0 0 0 10 0 70 0 0 0 0 % Q
% Arg: 0 0 0 60 0 60 0 10 70 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 60 0 0 0 0 0 0 20 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 0 90 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 20 0 20 0 10 0 10 0 0 0 0 0 0 70 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _