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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AXIN1 All Species: 15.76
Human Site: S623 Identified Species: 31.52
UniProt: O15169 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15169 NP_003493.1 862 95635 S623 S T E V P G A S E D A E K N Q
Chimpanzee Pan troglodytes XP_001152990 821 90810 S623 S T E V P G A S E D A E K N Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852321 867 95820 S623 S T E V P G P S E D T D K N Q
Cat Felis silvestris
Mouse Mus musculus O35625 863 96295 T619 N A E V P S T T E D A E K N Q
Rat Rattus norvegicus O70239 827 92266 T619 S A E V P S T T E D A E K N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508740 844 93228 A610 P G M P P L P A D E A D R S Q
Chicken Gallus gallus O42400 841 94913 P633 N Y E M P G S P E D V E R N Q
Frog Xenopus laevis Q9YGY0 842 94441 P633 S H E M P V V P E D S E R H Q
Zebra Danio Brachydanio rerio P57094 835 94310 A632 E M R E P L P A D D M E R N Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V407 745 81700 G550 D G A M S L S G H S M K H S K
Honey Bee Apis mellifera XP_001120373 693 78297 E501 R L L S W L K E T D K K A D I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781992 855 95982 M596 P R V Q N Q S M H H R Q R H R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.6 N.A. 86.6 N.A. 87 84.2 N.A. 43.2 73 67.5 64 N.A. 21.8 27.2 N.A. 33
Protein Similarity: 100 95.1 N.A. 91.2 N.A. 91.1 88.1 N.A. 59.4 82.9 79.4 74.8 N.A. 38 42.4 N.A. 50.3
P-Site Identity: 100 100 N.A. 80 N.A. 66.6 73.3 N.A. 20 53.3 46.6 33.3 N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 100 N.A. 86.6 N.A. 80 80 N.A. 60 80 73.3 53.3 N.A. 33.3 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 0 0 0 17 17 0 0 42 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 17 75 0 17 0 9 0 % D
% Glu: 9 0 59 9 0 0 0 9 59 9 0 59 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 17 0 0 0 34 0 9 0 0 0 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 17 9 0 0 9 17 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 9 17 42 0 9 % K
% Leu: 0 9 9 0 0 34 0 0 0 0 0 0 0 0 0 % L
% Met: 0 9 9 25 0 0 0 9 0 0 17 0 0 0 0 % M
% Asn: 17 0 0 0 9 0 0 0 0 0 0 0 0 59 0 % N
% Pro: 17 0 0 9 75 0 25 17 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 9 0 0 0 0 0 9 0 0 75 % Q
% Arg: 9 9 9 0 0 0 0 0 0 0 9 0 42 0 9 % R
% Ser: 42 0 0 9 9 17 25 25 0 9 9 0 0 17 0 % S
% Thr: 0 25 0 0 0 0 17 17 9 0 9 0 0 0 0 % T
% Val: 0 0 9 42 0 9 9 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _